Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 43.00 | |
5 mg | In stock | $ 93.00 | |
10 mg | In stock | $ 166.00 | |
25 mg | In stock | $ 277.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 95.00 |
Description | GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM |
Targets&IC50 | RET:0.4 nM |
In vitro | The effect of GSK3179106 on human and rat RET enzymatic activity and motesanib on human RET enzymatic activity was determined in an in vitro biochemical homogeneous time-resolved fluorescence (HTRF) assay. |
In vivo | GSK3179106 (3 or 10 mg/kg; orally; for 3.5 days BID) reduces the visceromotor response (VMR) in comparison to rats given an acetic acid enema and dosed with vehicle. |
Molecular Weight | 467.41 |
Formula | C22H21F4N3O4 |
CAS No. | 1627856-64-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (213.94 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GSK3179106 1627856-64-7 Apoptosis Tyrosine Kinase/Adaptors c-RET syndrome post-inflammatory visceral GSK-3179106 stress-induced irritable RET Inhibitor bowel hypersensitivity GSK 3179106 orally inhibit IBS inhibitor