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MCL0020

Catalog No. TP1889 CAS 475498-26-1

Synonyms: MCL 0020

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and < 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo.

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MCL0020, CAS 475498-26-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 237.00
5 mg	In stock	$ 592.00
10 mg	In stock	$ 845.00
25 mg	In stock	$ 1,280.00
50 mg	In stock	$ 1,730.00
100 mg	In stock	$ 2,330.00

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Purity: 99.18%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo.

Synonyms	MCL 0020
Molecular Weight	609.72
Formula	C34H39N7O4
CAS No.	475498-26-1

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

25% ethanol / water: 2 mg/mL

References and Literature

1. Chaki et al (2003) Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur.J.Pharmacol. 474 95 PMID:

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library GPCR Compound Library Inhibitor Library NO PAINS Compound Library Anti-Obesity Compound Library

Related Products

Related compounds with same targets

Neuropeptide EI, rat acetate Melanotan (MT)-II TCMCB07 PF-07258669 a-MSH, amide Acetate(581-05-5 free base) Bremelanotide Acetate HS 014 acetate(207678-81-7 free base) Bivamelagon hydrochloride

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MCL0020 475498-26-1 GPCR/G Protein Neuroscience Melanocortin Receptor inhibit COS-1 Inhibitor MC Receptor anorexia dose-dependently stress-induced MCL-0020 MCL 0020 inhibitor

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