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MCL0020

Catalog No. TP1889 CAS 475498-26-1

Synonyms: MCL 0020

Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo.

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MCL0020, CAS 475498-26-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 237.00
50 mg	In stock	$ 2,165.00
100 mg	In stock	$ 3,259.00

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Purity: 99.18%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	MCL 0020
Molecular Weight	609.731
Formula	C34H39N7O4
CAS No.	475498-26-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

25% ethanol / water: 2 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Chaki et al (2003) Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur.J.Pharmacol. 474 95 PMID:

Related compound libraries

This product is contained In the following compound libraries：

NO PAINS Compound Library GPCR Compound Library Neuronal Signaling Compound Library Inhibitor Library Peptide Compound Library

Related Products

Related compounds with same targets

HS 014 acetate(207678-81-7 free base) HS024 [D-Trp8]-γ-MSH acetate(321351-81-9 free base) Melanotan (MT)-II ACTH 11-24 acetate(4237-93-8 free base) α-MSH Adrenocorticotropic Hormone (ACTH) (4-10), human Bremelanotide Acetate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MCL0020 475498-26-1 GPCR/G Protein Neuroscience Melanocortin Receptor MCL 0020 inhibit COS-1 Inhibitor MC Receptor anorexia dose-dependently stress-induced MCL-0020 inhibitor

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