hik — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12256	NS8593 hydrochloride	NS8593 HCl	Potassium Channel
	NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .		Potassium Channel
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T16523L	PhiKan 083		Mdm2
	PhiKan 083 is a carbazole derivative		Mdm2
T9394	CHIKV-IN-2		Dehydrogenase
	CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec...		Dehydrogenase
TN1137	Isobutylshikonin		Others
	Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·.		Others
T5S2350	Beta-Acetoxyisovalerylshikonin	Acetoxyisovalerylalkannin	Others
	Acetoxyisovalerylshikonin, a naphthoquinone derivative extracted from Arnebia euchroma, is a chemical compound.		Others
T2739	Shikimic Acid	Shikimate	Others , Endogenous Metabolite
	Shikimic Acid (Shikimate) is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it.		Others , Endogenous Metabolite
T2897	(Rac)-Shikonin	(±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid	Others
	(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...		Others
TN2447	Isovalerylshikonin		Antibacterial
	Isovalerylshikonin is a natural product from Arnebia euchroma		Antibacterial
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
T5S2347	Deoxyshikonin	Arnebin 7	Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
	1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ...		Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
TN1295	5-O-Caffeoylshikimic acid		IL Receptor , TNF , NO Synthase
	5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.		IL Receptor , TNF , NO Synthase
TN1238	3,4-O-Isopropylidene-shikimic acid	3,4-O-Isopropylidene shikimic acid	NOS , NO Synthase
	3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by tri...		NOS , NO Synthase
T3863	Chikusetsusaponin IVa	Calenduloside F	AMPK
	Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used...		AMPK
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase
T1125	Shikonin	NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid	TNF , NF-κB , Chloride channel , HIV Protease , PKM
	Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.		TNF , NF-κB , Chloride channel , HIV Protease , PKM
TN2443	Chikusetsusaponin Ib	Chikusetsu saponin Ib	AChE
	Chikusetsusaponin Ib (Chikusetsu saponin Ib) is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.		AChE
TN3052	4-O-Caffeoylshikimic acid		Others
	4-O-Caffeoylshikimic acid is a natural product from Illicium verum.		Others
T126409	5-0-Galloylshikimicacid
	5-0-Galloylshikimicacid is a useful organic compound for research related to life sciences. The catalog number is T126409 and the CAS number is 110082-91-2.
T125229	Yashabushiketol
	Yashabushiketol is a useful organic compound for research related to life sciences. The catalog number is T125229 and the CAS number is 24192-00-5.