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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
T22671 | CJ 033466 | 5-HT Receptor | |
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect. | |||
T5051 | Isopropamide Iodide | AChR | |
Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t... | |||
T38612 | Linaprazan glurate | Others | |
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. | |||
T5S1172 | Tiliroside | Tribuloside | Antioxidant |
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati... | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T21422 | Methylnaltrexone bromide | Relistor,MOA-728,MOA 728,Methylnaltrexone,MOA728 | Opioid Receptor |
Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone bromide acts to reverse some of the side effects of opioid drugs such as constipation without af... | |||
T7022 | PEG300 | Polyethylene glycol 300 | Others |
PEG300 (Polyethylene glycol 300) is a polymer formed from repeating units of ethylene glycol that is water soluble, low immunogenicity, and biocompatible. PEG300 is a neutral polymer with a molecular weight of 300. | |||
T6935 | Nirogacestat | PF-03084014,PF-3084014,PF03084014,PF 03084014 | Apoptosis , Gamma-secretase |
Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay). | |||
T0794 | Mepenzolate Bromide | Colibantil,Cantil,Cantilaque | AChR |
Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions. | |||
T0199 | Cephradine | Anspor,Cephradin,Velosef,SQ-11436,Sefril | TOPK , Antibacterial , Antibiotic |
Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. | |||
T0700 | Ursodeoxycholic acid | UDCA,Ursodiol | Potassium Channel , Endogenous Metabolite |
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption. | |||
T1551 | Tegaserod maleate | HTF-919,SDZ-HTF-919 | 5-HT Receptor |
Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug ... | |||
T24047 | Etilevodopa hydrochloride | Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester | Others , Dopamine Receptor , Drug Metabolite |
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration. | |||
T1291 | Cisapride | Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase | Potassium Channel , 5-HT Receptor , HER |
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease... | |||
TP1793 | Nociceptin (1-13), amide | Opioid Receptor | |
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes. | |||
T16083 | Mizagliflozin | GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base | SGLT |
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that ca... | |||
T29078 | Ursodeoxycholic acid sodium | UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium | FXR , Endogenous Metabolite , GPCR19 |
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it... | |||
T13570 | Benzamide Derivative 1 | Others | |
Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases. | |||
T13997 | AU-224 | Others | |
AU-224 is an orally available benzamide derivative that is a potent gastrointestinal prokinetic. |