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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2467 | R406 free base | R406 (free base) | Apoptosis , FLT , Syk |
R406 free base (R406 (free base)) is a potent Syk inhibitor. | |||
T10353 | APX-115 free base | Ewha-18278 free base | NADPH-oxidase , NADPH |
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid... | |||
T38995 | Taletrectinib free base | AB-106freebase,Taletrectinib free base,IBI-344 free base,DS-6051b free base | ROS Kinase |
Taletrectinib free base (AB-106 free base) is a novel potent, selective and orally active ROS1/NTRK inhibitor.Taletrectinib free base has potent inhibitory effects on recombinant ROS1, NTRK1, NTRK2, and NTRK3, with IC50s... | |||
T70407 | Cemadotin free base | LU103793 free base | Microtubule Associated |
Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks mitosis and inhibits microtubules (tubulin) with a Ki of 1 μM. Ce... | |||
T11948 | Masupirdine free base | Masupirdine,SUVN-502 free base | 5-HT Receptor |
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier and has a Ki value of 2.04 nM for the human 5-HT6 receptor.Masupirdine free base is potent ... | |||
T12527L | Mavodelpar free acid hydrochloride | Mavodelpar free acid hydrochloride(942594-93-6 Free base),Pparδ agonist HCl,HPP593 free acid HCl,REN001 free acid HCl | PPAR |
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist. | |||
T71534L | CIA-1 (Free base) | CIA-1(Free base) | Gamma-secretase |
CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenogr... | |||
T39733 | Hu7691 free base | Akt | |
Hu7691 free base is an orally active, potent and selective Akt inhibitor with anti-proliferative and neurogenic effects on a variety of neuroblastoma cell lines.Hu7691 free base inhibits Akt1, Akt2, and Akt3 and induces ... | |||
TP2500 | Cholecystokinin (26-33) free acid | CCK (26-33) free acid | cholecystokinin |
Cholecystokinin (26-33) free acid, a part of cholecystokinin (CCK), is a highly selective ligand for CCKB-type receptors found in the vertebrate CNS and induces a mild taste aversion conditioned reflex in rats. | |||
T3627 | IQ-1S free acid | IQ-1,IQ-1S,IQ-1S (free acid) | NF-κB , JNK |
IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se... | |||
T11321 | FR194738 free base | Antifungal | |
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. | |||
TQ0122L | VCH-916 free acid(1200133-34-1 free base) | HCV Protease | |
VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor. | |||
T3480 | Sudoterb free base | Sudoterb | ATPase |
Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate. | |||
T6140 | SB-334867 free base | SB334867A free base,SB-334867,SB 334867,SB334867 | OX Receptor |
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist. | |||
T9642 | ZW4864 free base | Wnt/beta-catenin | |
ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor. ZW4864 (free base) inhibits β catenin/BCL9 PPI with a K i value of 0.76 μM an... | |||
T12056 | MK-0941 free base | Glucokinase | |
MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes. | |||
T11492 | GSK2983559 free acid | Others , RIP kinase | |
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammato... | |||
T10893 | CS-722 Free base | Others | |
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-... | |||
T22277L | BMS-P5 free base | PAD | |
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-... | |||
T4049 | Genz-123346 free base | Glucokinase | |
Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1. |