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GSK2983559 free acid

Catalog No. T11492   CAS 1579965-12-0

GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an

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GSK2983559 free acid Chemical Structure
GSK2983559 free acid, CAS 1579965-12-0
Pack Size Availability Price/USD Quantity
1 mg In stock $ 44.00
5 mg In stock $ 97.00
10 mg In stock $ 150.00
25 mg In stock $ 251.00
50 mg In stock $ 375.00
100 mg In stock $ 563.00
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Purity: 98.61%
Purity: 98.08%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an
Molecular Weight 538.53
Formula C21H23N4O7PS2
CAS No. 1579965-12-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4.5 mg/mL (8.36 mM), ultrasonic and warming and heat to 80°C

TargetMolReferences and Literature

1. Haile PA, et al. Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. J Med Chem. 2019 Jul 25;62(14):6482-6494.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library PPI Inhibitor Library Anti-Liver Cancer Compound Library Anti-Breast Cancer Compound Library Bioactive Compound Library Bioactive Compounds Library Max Inhibitor Library Pyroptosis Compound Library Anti-Ovarian Cancer Compound Library

Related Products

Related compounds with same targets
RIPK2-IN-3 GSK481 Tuxobertinib GSK2593074A SZM679 GSK3145095 SZM-1209 HS-1371

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Keywords

GSK2983559 free acid 1579965-12-0 Apoptosis NF-Κb Others RIP kinase inhibit THP-1 cell GSK 2983559 Inhibitor GSK-2983559 RIPK Receptor-interacting protein kinases GSK-2983559 free acid GSK2983559 inhibitor

 

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