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Search Results for " chemotherapy "

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Compounds

Cat No. Product Name Synonyms Targets
T2747 Endothall Others
Endothall is an effective protein phosphatase 2A (PP2A) inhibitor, exerting inhibitory effects on both PP2A and PP1, with IC50 values of 90 nM and 5 µM, respectively. It exhibits anticancer activity, making it suitable f...
T21876 DC_AC50 Apoptosis , Others
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin...
T22746 Tesmilifene fumarate DPPE fumarate Histamine Receptor
Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。
T9271 RAD51-IN-1 DNA/RNA Synthesis
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
T2217 Cephalomannine Baccatin III Microtubule Associated
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
T1564 Cisplatin cis-Diaminodichloroplatinum,CDDP DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.
T21936 M50054 Caspase
Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.
T1414 Sodium 2-mercaptoethanesulfonate Mitexan,Uromitexan,Mesna,Mesnum,Mesnex Others
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
T0132 Etoposide VP-16,VP-16-213 Apoptosis , Mitophagy , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
T1528 Azasetron hydrochloride Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl 5-HT Receptor
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.
T1478 Ondansetron hydrochloride dihydrate SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride 5-HT Receptor
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a...
T1790 Fosaprepitant dimeglumine L785298,MK-0517,Fosaprepitant dimeglumine salt Neurokinin receptor
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...
T2047 AG-1478 AG1478,NSC 693255,Tyrphostin AG-1478 EGFR , HCV Protease , Influenza Virus , HER , PDGFR
AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
T16871 Semustine DNA Alkylator/Crosslinker
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.
T6431 Levoleucovorin Calcium Calcium Levofolinate,CL307782 Others , Antifolate
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
T28187 Nonabine
Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.
T22286 Cyanosafracin B Cyanoquinonamine,CBR28-1 Others
Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug).
T39024 PrNMI Cannabinoid Receptor
PrNMI is a highly effective and orally active agonist targeting the peripherally restricted cannabinoid 1 receptor (CB1R). It exhibits pronounced analgesic properties, efficiently suppressing both chemotherapy-induced pe...
T21899 Misonidazole SR-1354,SR1354,Ro 7-0582 GPX
Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.
T22313 Dolasetron Mesylate Anzemet hydrate,MDL-73147EF Others , 5-HT Receptor
Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following chemotherapy.

Compounds

Endothall
T2747
Synonym:
Target: Others
DC_AC50
T21876
Synonym:
Target: Apoptosis, Others
Tesmilifene fumarate
T22746
Synonym: DPPE fumarate
Target: Histamine Receptor
RAD51-IN-1
T9271
Synonym:
Target: DNA/RNA Synthesis
Cephalomannine
T2217
Synonym: Baccatin III
Target: Microtubule Associated
Cisplatin
T1564
Synonym: cis-Diaminodichloroplatinum,CDDP
Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy
M50054
T21936
Synonym:
Target: Caspase
Sodium 2-mercaptoethanesulfonate
T1414
Synonym: Mitexan,Uromitexan,Mesna,Mesnum,Mesnex
Target: Others
Etoposide
T0132
Synonym: VP-16,VP-16-213
Target: Apoptosis, Mitophagy, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Azasetron hydrochloride
T1528
Synonym: Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl
Target: 5-HT Receptor
Ondansetron hydrochloride dihydrate
T1478
Synonym: SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride
Target: 5-HT Receptor
Fosaprepitant dimeglumine
T1790
Synonym: L785298,MK-0517,Fosaprepitant dimeglumine salt
Target: Neurokinin receptor
AG-1478
T2047
Synonym: AG1478,NSC 693255,Tyrphostin AG-1478
Target: EGFR, HCV Protease, Influenza Virus, HER, PDGFR
Semustine
T16871
Synonym:
Target: DNA Alkylator/Crosslinker
Levoleucovorin Calcium
T6431
Synonym: Calcium Levofolinate,CL307782
Target: Others, Antifolate
Nonabine
T28187
Synonym:
Target:
Cyanosafracin B
T22286
Synonym: Cyanoquinonamine,CBR28-1
Target: Others
PrNMI
T39024
Synonym:
Target: Cannabinoid Receptor
Misonidazole
T21899
Synonym: SR-1354,SR1354,Ro 7-0582
Target: GPX
Dolasetron Mesylate
T22313
Synonym: Anzemet hydrate,MDL-73147EF
Target: Others, 5-HT Receptor
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TargetMol