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Nonabine

Catalog No. T28187 CAS 16985-03-8

Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.

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Nonabine, CAS 16985-03-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 142.00
5 mg	In stock	$ 350.00
10 mg	In stock	$ 530.00
25 mg	In stock	$ 859.00
50 mg	In stock	$ 1,180.00
100 mg	In stock	$ 1,590.00

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Purity: 99.95%

Purity: 99.19%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.

In vivo

Nonabine is a chromenol structurally related to the cannabinoids which has shown antiemetic efficacy in clinical trials. Nonabine also produced sedative clinical effects, but with an EEG profile that resembled that reportedly caused by cannabinoids. In contrast to cannabinoids, nonabine did not cause changes of mood or perception, suggesting that nonabine lacks the potential for social abuse at antiemetic doses.[1]

Molecular Weight	379.54
Formula	C25H33NO2
CAS No.	16985-03-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (144.91 mM)

References and Literature

1. McClelland GR, et al. Pilot investigation of the quantitative EEG and clinical effects of ketazolam and the novel antiemetic nonabine in normal subjects. Psychopharmacology (Berl). 1985;85(3):306-8. 2. Staquet M, et al. Clinical studies with a THC analog (BRL-4664) in the prevention of cisplatin-induced vomiting. J Clin Pharmacol. 1981 Aug-Sep;21(8-9 Suppl):60S-63S. 3. Archer CB, et al. Antiemetic effect of nonabine in cancer chemotherapy: a double blind study comparing nonabine and chlorpromazine. Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):350-1.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Bioactive Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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Keywords

Nonabine 16985-03-8 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.