Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 45.00 | |
10 mg | In stock | $ 61.00 | |
25 mg | In stock | $ 114.00 | |
50 mg | In stock | $ 207.00 | |
100 mg | In stock | $ 288.00 | |
200 mg | In stock | $ 374.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor. |
Targets&IC50 | EGFR:3 nM |
Cell Research | Cells are exposed to different concentrations of AG-1478 for 72 hours in 96-well plates. The effects of AG-1478 on cell growth are examined using an Alamar Blue assay. A 20-μL aliquot of Alamar Blue is added to each well, and its absorbance is determined using a Spectromax Scanning Micro plate Reader. The effects of AG-1478 are expressed as percentage of growth inhibition using untreated cells as the control (0% inhibition). Cellular DNA synthesis is determined using a [3H]thymidine incorporation assay. (Only for Reference) |
Synonyms | AG1478, NSC 693255, Tyrphostin AG-1478 |
Molecular Weight | 315.75 |
Formula | C16H14ClN3O2 |
CAS No. | 153436-53-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 11 mg/mL (34.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 24 mg/mL (76 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AG-1478 153436-53-4 Angiogenesis JAK/STAT signaling Microbiology/Virology Proteases/Proteasome Tyrosine Kinase/Adaptors HCV Protease Influenza Virus EGFR PDGFR HER diseases encephalomyocarditis HCV virus HER1 obesity AG1478 cardiovascular myocardial NSC 693255 injury ErbB-1 EMCV Tyrphostin AG-1478 Hepatitis C virus antiviral AG 1478 NSC693255 Tyrphostin AG 1478 Epidermal growth factor receptor inhibit Inhibitor cancer NSC-693255 chemotherapy Tyrphostin AG1478 inhibitor