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Search Results for " calcium-activated "

20

Compounds

Cat No. Product Name Synonyms Targets
T13047 Synta66 Calcium Channel
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.
T10885 CRAC intermediate 2 Others , Calcium Channel
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
T3904 Gomisin J Calcium Channel , AMPK
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...
T24984 5J-4 Calcium Channel
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt.
T10884 CRAC intermediate 1 5-(S)-Fluorowillardiine Calcium Channel
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
T3651 YM-58483 YM 58483,BTP2 Calcium Channel
YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.
T9522 Rimtuzalcap CAD-1883 Potassium Channel
Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spin...
T8867 RO2959 Hydrochloride RO2959 HCl IL Receptor , Calcium Channel , Interleukin
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T5701 OPHIOPOGONIN D RAAS , Calcium Channel , NF-κB , PPAR
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
TQ0033 Zegocractin CM-4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM4620 Calcium Channel
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor.
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T2946 Tanshinone IIA sulfonate sodium Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium CaMK , P450 , Calcium Channel
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor...
T9245 TRPM4-IN-1 CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid TRP/TRPV Channel
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
T2170 SKF-96365 hydrochloride SKF96365 Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
T7512 BMS-191011 BMS-A Potassium Channel
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
T4330 CaCCinh-A01 Chloride channel
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T13059 T16Ainh-A01 Chloride channel
T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated chloride channel (CaCC).
T22946 LY255283 LY 255283 Leukotriene Receptor
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A2318...
T4411 DAMGO TFA (78123-71-4(Free base)) Opioid Receptor
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food int...

Compounds

Synta66
T13047
Synonym:
Target: Calcium Channel
CRAC intermediate 2
T10885
Synonym:
Target: Others, Calcium Channel
Gomisin J
T3904
Synonym:
Target: Calcium Channel, AMPK
5J-4
T24984
Synonym:
Target: Calcium Channel
CRAC intermediate 1
T10884
Synonym: 5-(S)-Fluorowillardiine
Target: Calcium Channel
YM-58483
T3651
Synonym: YM 58483,BTP2
Target: Calcium Channel
Rimtuzalcap
T9522
Synonym: CAD-1883
Target: Potassium Channel
RO2959 Hydrochloride
T8867
Synonym: RO2959 HCl
Target: IL Receptor, Calcium Channel, Interleukin
OPHIOPOGONIN D
T5701
Synonym:
Target: RAAS, Calcium Channel, NF-κB, PPAR
Zegocractin
TQ0033
Synonym: CM-4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM4620
Target: Calcium Channel
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Tanshinone IIA sulfonate sodium
T2946
Synonym: Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium
Target: CaMK, P450, Calcium Channel
TRPM4-IN-1
T9245
Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
Target: TRP/TRPV Channel
SKF-96365 hydrochloride
T2170
Synonym: SKF96365
Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy
BMS-191011
T7512
Synonym: BMS-A
Target: Potassium Channel
CaCCinh-A01
T4330
Synonym:
Target: Chloride channel
Ethosuximide
T0728
Synonym: Zarontin
Target: Calcium Channel
T16Ainh-A01
T13059
Synonym:
Target: Chloride channel
LY255283
T22946
Synonym: LY 255283
Target: Leukotriene Receptor
DAMGO TFA (78123-71-4(Free base))
T4411
Synonym:
Target: Opioid Receptor
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TargetMol