0-4℃ for short term (days to weeks), or -20℃ for long term (months).
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | 58.00 | |
10 mg | In stock | 107.00 | |
25 mg | In stock | 224.00 | |
50 mg | In stock | 400.00 | |
100 mg | In stock | 711.00 | |
200 mg | In stock | 995.00 | |
1 mL * 10 mM (in DMSO) | In stock | 64.00 |
Description | CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM). |
Targets&IC50 | TMEM16A, CaCC, |
Cell Research |
Each well of a 96-well plate is washed three times with PBS (200 μL/wash), leaving 50 μL of PBS. Test compounds (including CaCCinh-A01) (0.5 μL) are added to each well at 25 μM final concentration. After 10 min, 96-well plates are transferred to a plate reader for fluorescence assay. Each well is assayed individually for TMEM16A-mediated I- influx by recording fluorescence continuously (400 ms/point) for 2 s (baseline), then 50 μL of a 140 mM I-solution containing 200 μM ATP is added.
|
Molecular Weight | 347.43 |
Formula | C18H21NO4S |
CAS No. | 407587-33-1 |
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Safe and effective drug dosing is necessary, regardless of its purpose of administration. Learn More
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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.