Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 38.00 | |
10 mg | In stock | $ 61.00 | |
25 mg | In stock | $ 133.00 | |
50 mg | In stock | $ 226.00 | |
100 mg | In stock | $ 363.00 | |
200 mg | In stock | $ 529.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 67.00 |
Description | TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM. |
Targets&IC50 | TRPM4:1.5 μM |
In vitro | TRPM4-IN-1 selectively inhibits TRPM4 overexpressed in HEK293 cells. TRPM4-IN-1 inhibits endogenous TRPM4 currents in LNCaP cells. TRPM4-IN-1 restores functional expression of A432T, a loss‐of‐expression TRPM4 variant. |
Synonyms | CBA, 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid |
Molecular Weight | 340.16 |
Formula | C15H11Cl2NO4 |
CAS No. | 351424-20-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL(235.18 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TRPM4-IN-1 351424-20-9 Membrane transporter/Ion channel TRP/TRPV Channel TRP Channel Transient receptor potential channels non-selective TRPM4IN1 diseases TRPM4 CBA inhibit Inhibitor TRPM-4-IN-1 TRPM4 IN 1 cancer cation cardiac 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid channel prostate calcium-activated inhibitor