aminotransferase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76178	Aspartate aminotransferase
	Aspartate aminotransferase (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate am...
T78364	Alanine aminotransferase		Endogenous Metabolite
	Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-glutamate [1].		Endogenous Metabolite
T8765	IGOT1-01		Others
	iGOT1-01 is an effective inhibitor of glutamate oxaloacetate transaminase 1(GOT1) . iGOT1-01 has IC50s of 84.6 μM and 11.3 μM in GOT1/MDH1 assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 can be used in anti-cancer ...		Others
T8648	6-AZATHYMINE		Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis , Antibacterial
	6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic...
T8766	GOT1 inhibitor-1	GOT1 inhibitor 2c	Others
	GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.		Others
T7045	Clonidine	Nexiclon,Catapres,Kapvay	Adrenergic Receptor
	Clonidine (Kapvay) is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many years, clonidine has not been l...		Adrenergic Receptor
T67865	BJJF078		Glutaminase
	BJJF078, an aminopiperidine derivative, is a potent inhibitor of recombinant human and mouse glutamine aminotransferase (TG2) activity, with IC50 values of 41 and 54 nM for human and mouse glutamine aminotransferase, res...		Glutaminase
T26399	7-Methyl-6-mercaptopurine	7-Methyl-6-thiopurine,6-Mercapto-7-methylpurine	Others
	7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) is an inhibitor of PRPP aminotransferase, inhibits IMP metabolism and prevents purine, DNA and RNA synthesis.		Others
T67842	ERG240	EGR240	Others
	ERG240 is an inhibitor of branched-chain amino acid aminotransferase 1 (BCAT1). ERG240 can be used for the research of rheumatoid arthritis, cancer, and bone disease.		Others
T35868	BCAT-IN-2		Others
	BCAT-IN-2 is an orally active and selective inhibitor of mitochondrial branched-chain aminotransferase (BCATm), inhibits BCATm and BCATc, and is used in obesity and dyslipidemia.		Others
T1356	4-Hydroxy-3-methoxybenzylamine hydrochloride	N-Vanillylamine hydrochloride	Others
	4-Hydroxy-3-methoxybenzylamine hydrochloride (N-Vanillylamine hydrochloride) is an alkaloid that is an intermediate in the biosynthesis of capsaicin. 4-Hydroxy-3-methoxybenzylamine hydrochloride is produced from vanillin...		Others
T0180	Benazepril hydrochloride	CGS 14824A HCl,Benazepril HCl,CGS14824A	RAAS
	Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril hydrochloride is associated with a low rate of transient serum aminotra...		RAAS
T0805	Quinapril hydrochloride	CI-906,PD-109452-2,Quinapril HCl	RAAS
	Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie...		RAAS
T2395	Vortioxetine	Lu AA 21004	5-HT Receptor , Serotonin Transporter
	Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.		5-HT Receptor , Serotonin Transporter
T0710	L-Cycloserine	Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone	HIV Protease , GABA Receptor
	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...		HIV Protease , GABA Receptor
T1189	Milnacipran hydrochloride	Milnacipran HCl,Savella,Dalcipran	Serotonin Transporter , Norepinephrine
	Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy...		Serotonin Transporter , Norepinephrine
T0078L	Lapatinib ditosylate monohydrate	Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb	EGFR , Ferroptosis , Autophagy
	Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w...		EGFR , Ferroptosis , Autophagy
T0137	Mirtazapine	6-Azamianserin,Org3770	Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor
	Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h...
T4297	Flibanserin	BIMT-17BS,Girosa,BIMT-17	Dopamine Receptor , 5-HT Receptor
	Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...		Dopamine Receptor , 5-HT Receptor
T0192	Levetiracetam	UCB L059,SIB-S1	DNA Methyltransferase , Others , Calcium Channel
	Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been linked to rare instances of serum...		DNA Methyltransferase , Others , Calcium Channel