uptake — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15130	Dilazep dihydrochloride		Others
	Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc...		Others
T9031	MCU-i4		Others , Mitochondrial Metabolism
	MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.		Others , Mitochondrial Metabolism
T11064	DMT1 blocker 2		Others
	DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo.		Others
T4534	BMS-309403		FABP
	BMS-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM.		FABP
T15802	LY2183240		FAAH , Autophagy
	LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM).		FAAH , Autophagy
T5345	V-9302		Others
	V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).		Others
T23070	Nisoxetine hydrochloride		Sodium Channel , Monoamine Transporter , Norepinephrine
	Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor		Sodium Channel , Monoamine Transporter , Norepinephrine
T5799	Arecaidine hydrochloride		Others
	Arecaidine hydrochloride may have carcinogenesis.		Others
T12931	SLC13A5-IN-1		Stearoyl-CoA Desaturase (SCD)
	SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).		Stearoyl-CoA Desaturase (SCD)
T11908	LY2365109 hydrochloride		GlyT
	LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.		GlyT
T14327	AS1949490		Phosphatase
	AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.		Phosphatase
T14496	BAMB-4	ITPKA-IN-C14	Others
	BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in...		Others
T12306	OMDM-5		Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel
	OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
T39429	AHN 1-055 hydrochloride	3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride	Dopamine Receptor
	AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).		Dopamine Receptor
T19931	Gentisein	NSC 329491,NSC329491,NSC-329491	Serotonin Transporter
	Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].		Serotonin Transporter
T8702	SKF-83566		Dopamine Receptor , 5-HT Receptor , AChR
	SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM		Dopamine Receptor , 5-HT Receptor , AChR
TL0006	Cichoric Acid	Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species , HIV Protease
	Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...		Reactive Oxygen Species , HIV Protease
T3470	Cis-ACBD	cis-1-aminocyclobutane-1,3-dicarboxylic acid	Amino Acids and Derivatives
	Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.		Amino Acids and Derivatives
T9352	Hydrocotarnine		Others
	hydrocotarnine is an inhibitor of Cbl.		Others
T1233	Oxolinic acid	Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox	Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.