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Search Results for " nf-kappab-in-2 "

10

Compounds

Cat No. Product Name Synonyms Targets
T60357 NF-κB-IN-2 JEUD-38
NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNFin PC-3 cells.
T3829 Ginsenoside F3 Others , IFNAR , Interleukin
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...
TN6694 5,6-Benzoflavone β-Naphthoflavone,beta-NF Antioxidant
5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...
T6S0119 Dauricine Apoptosis , Others , NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...
T7033 Rosmanol Antioxidant , COX
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a...
T28749 SEMBL
SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.
TN5019 Siegeskaurolic acid TNF , NOS , NF-κB , COX , NO Synthase , Prostaglandin Receptor
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation.
TN4046 Excisanin A MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm...
TN2775 2-Methoxystypandrone MMP , BCL , IκB/IKK , GSK-3 , TNF , NOS , NF-κB , Wnt/beta-catenin , COX , JAK , STAT
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrit...
TN3708 Coronarin D BCL , c-Myc , TNF , NF-κB , Caspase , COX , Antifection
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active again...
TargetMol