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Search Result

Search Results for " il-7 "

Targets

IRAK

14

Compounds

5

Natural Products

36

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T5354 IRAK4-IN-7 CA-4948 IRAK
IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
T9948 NecroX-7 LC-280126,LC28-0126,LC28 0126 NADPH-oxidase
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ...
T25150 BI-69A11 BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one NF-κB , Akt
BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...
TP2015L HS 014 acetate(207678-81-7 free base) Melanocortin Receptor
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and no...
T13232 TyK2-IN-2 PDE
TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).
T70463 FCE-27164
FCE-27164 is a therapeutic agent that inhibits platelet-derived growth factor beta and IL-7 binding to their receptors.
T77171 Efineptakin alfa
Efineptakin alfa (NT-17), a long-acting recombinant human interleukin-7 (IL-7), promotes the proliferation and survival of CD4+ and CD8+ cells in both humans and mice. It has applications in glioblastoma research [1].
T78168 NLRP3-IN-17 NOD-like Receptor (NLR)
NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for...
T61823 Anticancer agent 63
Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 2...
T37564 C4 Ceramide (d18:1/4:0) C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used...
T71651 GSK1370319A
GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and caspase 1 activation in lipopolysaccharide (LPS)-primed mixed glia by blocking assembly of the infla...
T35927 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide (d18:1/2:0)
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration o...
T35451 β-Defensin-2 (human) (trifluoroacetate salt)
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...
T13172L TMP778 Others
TMP778 is an effective and selective RORγt inverse agonist (IC50: 7 nM in FRET assay).
Cat No. Product Name Synonyms Targets
TN1787 Isomucronulatol 7-O-glucoside Isomucronulatol 7-O-beta-glucoside Others
Isomucronulatol 7-O-glucoside is a natural product
TN6778 Umbelliprenin 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin IL Receptor
Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) alleviated neuropathic pain, and decreased serum IL-6 levels and oxidative stress.
T2S0843 Negletein 7-O-Methylbaicalein,Baicalein-7-methylether IL Receptor , TNF , NOS , Interleukin
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...
T4115 Auraptene 7-geranyloxycoumarin MMP , BACE
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...

Natural Products

Isomucronulatol 7-O-glucoside
TN1787
Synonym: Isomucronulatol 7-O-beta-glucoside
Target: Others
Umbelliprenin
TN6778
Synonym: 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin
Target: IL Receptor
Negletein
T2S0843
Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether
Target: IL Receptor, TNF, NOS, Interleukin
Auraptene
T4115
Synonym: 7-geranyloxycoumarin
Target: MMP, BACE
Oroxylin A
T6S1315
Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Recombinant Proteins

Species：
Human (25)
Mouse (7)
Cynomolgus (2)
Bovine (1)
Rat (1)
Expression System：
HEK293 Cells (26)
E. coli (9)
Baculovirus Insect Cells (1)
Tag：
Tag Free (7)
C-hFc (6)
C-His (4)
C-His-Avi (4)
His (3)
C-6xHis (2)
C-hFc-6xHis (2)
His, Avi (2)
C-hhFc (1)
N-6xHis (1)
Cat No. Product Name Species Expression System
TMPY-00524 IL-7 Protein, Mouse, Recombinant Mouse E. coli
IL-7 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is P10168.
TMPY-03383 IL-7 Protein, Human, Recombinant Human E. coli
IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1.
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPJ-00059 IL-7 Protein, Human, Recombinant (His) Human HEK293 Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions...
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1.
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPJ-00284 IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly...
TMPY-01367 IL-7R alpha/CD127 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16872.
TMPY-00400 IL-17B Protein, Human, Recombinant (hFc) Human Baculovirus Insect Cells
IL-17B Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is Q9UHF5.
TMPY-06312 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.76 kDa and the accession number is NP_003844.1.
TMPY-01200 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is O95256-1.
TMPY-06316 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.04 kDa and the accession number is NP_003844.1.
TMPK-00514 IL-18RAP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-18RAP, also known as IL-18Rβ or IL-1R7, is component of IL-18 receptor complex and its interactions with IL-18R1 mediate signal transduction initiated by IL-18 although it does not directly bind IL-18 in vitro.
TMPY-05377 IL-7R alpha/CD127 Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is P16871-1.
TMPY-06580 IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.14 kDa and the accession number is P16871-1.
TMPJ-00285 IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly...
TMPY-04042 IL-7 Protein, Rat, Recombinant Rat E. coli
IL-7 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q91Y32.
TMPH-00281 IL-7 Protein, Bovine, Recombinant (His) Bovine E. coli
Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL-7 Protein, Bovine, Recombinant (His) is expre...
TMPK-00060 IL-17B Protein, Mouse, Recombinant (His) Mouse E. coli
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/...
TMPJ-00344 IL-18RAP Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 a...
TMPJ-00042 TSLP Protein, Human, Recombinant Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of t...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
TMPJ-00239 IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc) Mouse HEK293 Cells
The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) pop...
TMPY-02597 IL-37 Protein, Human, Recombinant Human E. coli
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPY-02549 GBP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex...
TMPJ-00760 CXCL7 Protein, Human, Recombinant Human E. coli
Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domai...
TMPJ-00177 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated Human HEK293 Cells
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), T...
TMPJ-00952 CXCL12 Protein, Mouse, Recombinant Mouse E. coli
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, an...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 ...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.
IL-7 Protein, Mouse, Recombinant
TMPY-00524
Species: Mouse
Expression System: E. coli
IL-7 Protein, Human, Recombinant
TMPY-03383
Species: Human
Expression System: E. coli
IL-7 Protein, Mouse, Recombinant (His)
TMPJ-00038
Species: Mouse
Expression System: HEK293 Cells
IL-7 Protein, Human, Recombinant (His)
TMPJ-00059
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
TMPY-01446
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
TMPY-01209
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
TMPJ-00284
Species: Mouse
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His)
TMPY-01367
Species: Mouse
Expression System: HEK293 Cells
IL-17B Protein, Human, Recombinant (hFc)
TMPY-00400
Species: Human
Expression System: Baculovirus Insect Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06312
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)
TMPY-01200
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06316
Species: Human
Expression System: HEK293 Cells
IL-18RAP Protein, Cynomolgus, Recombinant (His)
TMPK-00514
Species: Cynomolgus
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)
TMPY-05377
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06580
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)
TMPJ-00285
Species: Human
Expression System: HEK293 Cells
IL-7 Protein, Rat, Recombinant
TMPY-04042
Species: Rat
Expression System: E. coli
IL-7 Protein, Bovine, Recombinant (His)
TMPH-00281
Species: Bovine
Expression System: E. coli
IL-17B Protein, Mouse, Recombinant (His)
TMPK-00060
Species: Mouse
Expression System: E. coli
IL-18RAP Protein, Human, Recombinant (hFc & His)
TMPJ-00344
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant
TMPJ-00042
Species: Human
Expression System: E. coli
TSLPR Protein, Cynomolgus, Recombinant (His)
TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293 Cells
IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)
TMPJ-00239
Species: Mouse
Expression System: HEK293 Cells
IL-37 Protein, Human, Recombinant
TMPY-02597
Species: Human
Expression System: E. coli
GBP1 Protein, Human, Recombinant (His)
TMPY-02549
Species: Human
Expression System: HEK293 Cells
CXCL7 Protein, Human, Recombinant
TMPJ-00760
Species: Human
Expression System: E. coli
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
TMPJ-00177
Species: Human
Expression System: HEK293 Cells
CXCL12 Protein, Mouse, Recombinant
TMPJ-00952
Species: Mouse
Expression System: E. coli
IGFBP-7 Protein, Human, Recombinant (hFc)
TMPK-01371
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00394
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
TMPK-00828
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00393
Species: Human
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
TMPY-06035
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L7600 Chemokine Inhibitor Library

59 compounds
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

Chemokine Inhibitor Library
L7600
Compounds: 59
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