Powder: -20°C for 3 years
In solvent: -80°C for 2 years
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus.
Description | HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. |
Molecular Weight | 1623.83 |
Formula | C73H98N20O19S2 |
CAS No. | TP2015L |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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HS 014 acetate(207678-81-7 free base) TP2015L GPCR/G Protein Neuroscience Melanocortin Receptor HS 014 acetate(207678 81 7 free base) HS 014 acetate(207678817 free base) Inhibitor inhibitor inhibit