Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
Pack Size | Availability | Price/USD | Quantity |
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1 mg | Inquiry | $ 278.00 |
Description | C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells. |
Synonyms | C2 L-threo Ceramide (d18:1/2:0) |
Molecular Weight | 341.53 |
Formula | C20H39NO3 |
CAS No. | 143615-69-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 5 mg/mL
DMSO: Soluble
Chloroform: Soluble
Ethanol: Soluble
You can also refer to dose conversion for different animals. More
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