gra — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3422	GRA Ex-25	GRA-Ex-25	Glucagon Receptor
	GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.		Glucagon Receptor
T5802	Stearyl glycyrrhetinate		Antiviral , Antibacterial
	Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.		Antiviral , Antibacterial
T35340	Bictegravir Sodium	GS-9883 Sodium	HIV Protease
	Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity		HIV Protease
T8745	PROTAC BRAF-V600E degrader-1	Compound 23	Raf
	PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.		Raf
TQ0291	Firategrast	SB 683699	Integrin
	Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...		Integrin
T6300	Degrasyn	WP1130	Apoptosis , JAK , Bcr-Abl , DUB , Autophagy
	Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcri...		Apoptosis , JAK , Bcr-Abl , DUB , Autophagy
T10413	Autogramin-1		mTOR , Autophagy
	Autogramin-1 potently inhibits autophagy induced by either mTORC1 inhibition (Rapamycin; IC50: 0.44 μM) or starvation (IC50: 0.17 μM).		mTOR , Autophagy
T13722	Homo-PROTAC pVHL30 degrader 1		Others , Ligand for E3 Ligase
	Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.		Others , Ligand for E3 Ligase
T9013	Autogramin-2	tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate	Autophagy
	Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50...		Autophagy
TN7026	Acorus gramineus, ext.		Others
	Acorus gramineus, ext is a natural product isolated from Acorus gramineus.		Others
TN7091	Isolugrandoside		Others
	Isolugrandoside is from the aerial parts of Digitalis davisiana Heywood.		Others
T3884	Neoandrographolide	Neoandrographiside	NOS , COX
	Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN...		NOS , COX
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
TN6705	Graveoline	2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine	Autophagy
	Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells		Autophagy
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
	Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.		IL Receptor , TNF
T9218	Andrograpanin	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE	p38 MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.		p38 MAPK
T1042	Granisetron hydrochloride	BRL 43694A,Granisetron HCl	5-HT Receptor
	Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.		5-HT Receptor
TJS1748	Methyl protogracillin		Antifection
	Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.		Antifection
T1130	Gramicidin	Gramicidinum,Gramicidine,Gramicidina	MRP , Antibacterial , Antibiotic
	A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTH...		MRP , Antibacterial , Antibiotic