Search Result

Search Results for " f10 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T9973	FAK-IN-7		FAK
	FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.		FAK
T4308	F1063-0967		Phosphatase
	F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.		Phosphatase
T3963	VUF10460		Histamine Receptor
	VUF10460 is a non-imidazole histamine H4 receptor agonist.		Histamine Receptor
T61112	SLF1081851		LPL Receptor
	SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.		LPL Receptor
T24949	VUF10132	VUF-10132,VUF 10132
	VUF10132 is a full inverse CXCR3 N3.35A agonist.
T29448	50F10	50 F 10,50-F-10
	50F10 is a stabilizer for the active LPL dimer. It can act by preventing angptl4- and heat-induced inactivation of LPL and reducing postprandial triglyceride levels.
T70591	PF1070A
	PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.
T24769	Scaff10-8	Scaff 10 8,Scaff-10-8
	Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
T62851	SLF1081851 TFA
	SLF1081851 (TFA) is a Spns2 inhibitor with an IC50 value of 1.93 μM for inhibition of S1P release.SLF1081851 (TFA) plays a key role in development and the immune system.
T27371	FR-167356	FR167356,FR 167356	ATPase
	FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces b...		ATPase
T37586	DMHAPC-Chol
	DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B...
T36460	CAY10736	CAY10736
	CAY10736 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal ...
T36497	CAY10735	CAY10735
	CAY10735 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 μM). CAY10735 inhibits migration of and the epithelial-to-mese...
T83886	IcFSP1 TFA
	icFSP1, an inhibitor of ferroptosis suppressor protein 1 (FSP1), promotes condensation and phase separation of FSP1 in cellular environments at 2.5 µM concentration but does not affect FSP1's enzymatic function in cell-f...
T79711	Antitumor photosensitizer-4		Apoptosis
	Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen speci...		Apoptosis
T79528	SWS1		PD-1/PD-L1
	SWS1, a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating anti-tumor efficacy, as evidenced by a 66.1% tumor growth inhibi...		PD-1/PD-L1
T78958	Anticancer agent 106		Apoptosis
	Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma, suggesting its utility in the study of cancer, particularly l...		Apoptosis
T79705	LP23		PD-1/PD-L1
	LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/Jurkat T cells and induction of HepG2 cell death. Additionally, LP2...		PD-1/PD-L1
T38320	93-O17S	93-O17S
	93-O17S is a chalcogen-containing cationic lipidoid.1It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing ...
T36138	BMP-22
	BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 (0.1-1,000 nM) inhibits autotaxin-mediated production of lysophosphatidic acid...
T37722	Diprovocim-1
	Diprovocim-1 is an agonist of the toll-like receptor 1/2 heterodimer.1It induces TNF-α release in THP-1 cells (EC50= 110 pM), an effect that can be inhibited by anti-TLR1 or anti-TLR2 antibodies. Diprovocim-1 (10 mg/kg) ...
T36181	Quinaldopeptin
	Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/...
T78855	Anticancer agent 157		NO Synthase
	Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, ...		NO Synthase
T83775	STING Agonist 12L	Stimulator of Interferon Genes Agonist 12L
	STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...
T83765	Dendrogenin A	DDA
	Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest...
T36645	CAY10763	CAY10763
	CAY10763 is a dual inhibitor of indolamine 2,3-dioxygenase 1 (IDO1; IC50= 46 nM) and STAT3 activation.1It binds to STAT3 (Kd= 530 nM) and selectively reduces the levels of STAT3 phosphorylated at the tyrosine in position...

Compounds

Target: Histamine Receptor

Synonym: VUF-10132,VUF 10132

Target:

50F10

T29448

Synonym: 50 F 10,50-F-10

Synonym: Scaff 10 8,Scaff-10-8

Synonym: FR167356,FR 167356

Antitumor photosensitizer-4

Synonym: Stimulator of Interferon Genes Agonist 12L

Cat No.	Product Name	Targets
T19328	Fructo-oligosaccharide DP11/GF10	Others
	Fructo-oligosaccharide DP11/GF10 is a fructooligosaccharide (FOS) compound with a degree of polymerization (DP) equal to 11. FOS consists of 10 fructose units connected by (2→1)-β-glycosidic bonds, with a single D-glucos...	Others
TN4085	Fupenzic acid	Others
	Fupenzic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin.	Others
TN5212	Uvedalin	Others
	Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.	Others
TN6054	Norglaucine hydrochloride
	(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and...
TN2792	2-Oxopomolic acid
	2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-Oxopomolic acid shows radical-scavenging activities similar t...

Natural Products

Fructo-oligosaccharide DP11/GF10

Norglaucine hydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00707	Coagulation factor X/F10 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin ...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPK-00249	TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPK-00277	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol...
TMPJ-01214	ZNF100 Protein, Human, Recombinant (His)	Human	E. coli
	Zinc Finger Protein 100 (ZNF100) is part of the krueppel C2H2-type zinc-finger protein family. ZNF100 contains 12 C2H2-type zinc fingers and 1 KRAB domain. ZNF100 is a DNA-binding protein domain consisting of zinc finger...
TMPJ-00418	TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-ri...
TMPK-00706	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
TMPJ-00430	TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-30 KDa and the accession number is A0A2K5TXK0.
TMPK-00707	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
TMPJ-00030	IL-1F10 Protein, Human, Recombinant	Human	E. coli
	Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate immune responses. IL-1F10 was expressed in fetal skin, spleen ...
TMPK-00708	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing norma...
TMPY-04301	MEGF10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MEGF10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 90.2 kDa and the accession number is Q96KG7-1.
TMPJ-00275	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 18-25 KDa and the accession number is O14763.
TMPY-02944	TRAIL/TNFSF10 Protein, Rhesus, Recombinant	Rhesus	E. coli
	TRAIL/TNFSF10 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.6 kDa and the accession number is F6S9W7.
TMPK-00276	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting d...
TMPY-02233	TRAIL/TNFSF10 Protein, Human, Recombinant	Human	E. coli
	TRAIL/TNFSF10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P50591.
TMPK-00248	TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPJ-00245	TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated	Mouse	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 20-40 KDa and the accession number is Q9QZM4.
TMPJ-00276	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 49 KDa and the accession number is O14763.
TMPY-00293	Influenza A H9N2 (A/Guinea fowl/Hong Kong/WF10/99) Hemagglutinin/HA Protein (His)	H9N2	Baculovirus Insect Cells
	Influenza A H9N2 (A/Guinea fowl/Hong Kong/WF10/99) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is Q80KD9.
TMPY-05162	MEGF10 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MEGF10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 90.2 kDa and the accession number is XP_016865476.1.
TMPY-04175	IL-1F10 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	IL-1F10 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.4 kDa and the accession number is AAK68048.1.
TMPJ-00655	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His）	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TN...
TMPJ-00246	TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4.
TMPH-02737	IL-1F10 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	IL-1F10 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-02784	TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His)	Mouse	E. coli
	TRAIL/TNFSF10 Protein, Mouse, Recombinant (aa 118-291, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.2 kDa and the accession number is P50592.
TMPY-01626	Influenza A H9N2 (A/Guinea fowl/Hong Kong/WF10/99) Hemagglutinin/HA1 Protein (His)	H9N2	HEK293 Cells
	Influenza A H9N2 (A/Guinea fowl/Hong Kong/WF10/99) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is Q80KD9.
TMPJ-00301	Coagulation Factor X Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a...