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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2747 | Endothall | Others | |
Endothall is an effective protein phosphatase 2A (PP2A) inhibitor, exerting inhibitory effects on both PP2A and PP1, with IC50 values of 90 nM and 5 µM, respectively. It exhibits anticancer activity, making it suitable f... | |||
T21876 | DC_AC50 | Apoptosis , Others | |
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.DC_AC50 binding to Atox1 and CCS and reducin... | |||
T22746 | Tesmilifene fumarate | DPPE fumarate | Histamine Receptor |
Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。 | |||
T9271 | RAD51-IN-1 | DNA/RNA Synthesis | |
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51. | |||
T2217 | Cephalomannine | Baccatin III | Microtubule Associated |
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity. | |||
T1564 | Cisplatin | cis-Diaminodichloroplatinum,CDDP | DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy |
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy. | |||
T21936 | M50054 | Caspase | |
Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition. | |||
T1414 | Sodium 2-mercaptoethanesulfonate | Mitexan,Uromitexan,Mesna,Mesnum,Mesnex | Others |
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide. | |||
T0132 | Etoposide | VP-16,VP-16-213 | Apoptosis , Mitophagy , Topoisomerase , Antibacterial , Antibiotic , Autophagy |
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy. | |||
T1528 | Azasetron hydrochloride | Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl | 5-HT Receptor |
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic. | |||
T1478 | Ondansetron hydrochloride dihydrate | SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride | 5-HT Receptor |
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a... | |||
T1790 | Fosaprepitant dimeglumine | L785298,MK-0517,Fosaprepitant dimeglumine salt | Neurokinin receptor |
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... | |||
T2047 | AG-1478 | AG1478,NSC 693255,Tyrphostin AG-1478 | EGFR , HCV Protease , Influenza Virus , HER , PDGFR |
AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor. | |||
T16871 | Semustine | DNA Alkylator/Crosslinker | |
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia. | |||
T28187 | Nonabine | ||
Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy. | |||
T6431 | Levoleucovorin Calcium | Calcium Levofolinate,CL307782 | Others , Antifolate |
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant. | |||
T22286 | Cyanosafracin B | Cyanoquinonamine,CBR28-1 | Others |
Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug). | |||
T39024 | PrNMI | Cannabinoid Receptor | |
PrNMI is a highly effective and orally active agonist targeting the peripherally restricted cannabinoid 1 receptor (CB1R). It exhibits pronounced analgesic properties, efficiently suppressing both chemotherapy-induced pe... | |||
T21899 | Misonidazole | SR-1354,SR1354,Ro 7-0582 | GPX |
Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors. | |||
T22313 | Dolasetron Mesylate | Anzemet hydrate,MDL-73147EF | Others , 5-HT Receptor |
Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following chemotherapy. |