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Cat No. | Product Name | Synonyms | Targets |
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T13194 | CSF1R-IN-2 | c-Fms , c-Met/HGFR , Src | |
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively). | |||
T4315 | Ki20227 | c-Fms , VEGFR , CSF-1R , PDGFR , c-Kit | |
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR2(IC50: 12 nM) and c-Kit/PDGFRβ(IC50: 451/217 nM), respectively. | |||
T2624 | OSI-930 | OSI 930 | Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit |
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors. | |||
T76868 | Lacnotuzumab | ||
Lacnotuzumab (MCS110), a humanized IgG1/κ monoclonal antibody, neutralizes and inhibits the interaction between CSF-1 and its receptor, CSF-1R. It is utilized in researching pigmented villonodular synovitis [1] [2]. | |||
T10644 | C-Fms-IN-10 | Others | |
c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity. | |||
T77116 | Plonmarlimab | ||
Plonmarlimab (TJ003234), an anti-GM-CSF monoclonal antibody, is utilized in researching rheumatoid arthritis and COVID-19 [1] [2]. | |||
T77025 | Gimsilumab | ||
Gimsilumab (MORAb-022), a humanized anti-GM-CSF monoclonal antibody, shows promise in the research of COVID-19 and rheumatoid arthritis (RA) [1] [2]. | |||
T76908 | Anumigilimab | ||
Anumigilimab (CSL-324) is a humanized IgG2a monoclonal antibody (mAb) targeting the human granulocyte colony-stimulating factor (G-CSF) receptor, utilized to elevate neutrophil counts at inflammation sites [1] [2]. | |||
T76915 | Axatilimab | ||
Axatilimab (SNDX-6352), a humanized IgG4 antibody that binds with high affinity to CSF-1R, is utilized in the study of chronic graft versus host disease (cGVHD) and various neoplastic diseases [1] [2]. | |||
T76751 | Lenzilumab | ||
Lenzilumab (KB 003) is a humanized monoclonal antibody designed to target CSF2/GM-CSF, with applications in COVID-19 and studies on chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) [1] [... | |||
T73659 | HLF1-11 | ||
HLF1-11, derived from human lactoferrin, serves as a broad-spectrum antimicrobial agent. It not only inhibits human MPO (myeloperoxidase) activity but also influences GM-CSF (granulocyte-macrophage colony-stimulating fac... | |||
T37800 | PF-04449613 | ||
PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor (IC50= 22 nM).1It is selective for PDE9A over PDE1C (IC50= >1,000 nM), as well as over a variety of other PDEs, inhibiting PDE2-8, -10, and -11 activity by less tha... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5224 | 2-Hydroxyhexanoic acid | 2-Hydroxycaproic acid | Others , Endogenous Metabolite |
2-Hydroxyhexanoic acid (2-Hydroxycaproic acid) is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hydroxyhexanoic acid is the most sign... | |||
T4819 | Pipecolic acid | (±)-Piperidine-2-carboxylic acid,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline | Others , Endogenous Metabolite , Antibacterial |
Pipecolic acid (2-Piperidinecarboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00750 | GM-CSF/CSF2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-03858 | GM-CSF/CSF2 Protein, Human, Recombinant | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPJ-01465 | GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) | Human | E.coli |
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of... | |||
TMPY-01037 | CSF1R Protein (Met1-Glu512), Human, Recombinant (His) | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-04114 | GM-CSF/CSF2 Protein, Mouse, Recombinant | Mouse | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-03662 | GM-CSF/CSF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-01065 | GM-CSFR alpha Protein, Human, Recombinant (His) | Human | HEK293 |
CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification... | |||
TMPY-02466 | GM-CSF/CSF2 Protein, Human, Recombinant (His) | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-05236 | GM-CSF/CSF2 Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPK-00414 | M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain ... | |||
TMPY-04938 | CSF1R Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPK-00415 | M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain ... | |||
TMPK-00656 | M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain ... | |||
TMPY-05436 | CSF1R Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-01833 | CSF1R Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-05045 | CSF1R Protein, Human, Recombinant (Domain I&II&III, His) | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-05429 | CSF1R Protein, Human, Recombinant (hFc) | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-00881 | CSF1R Protein, Human, Recombinant | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-04358 | CSF1R Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-06384 | CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-05513 | CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-03631 | GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-06389 | CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-05264 | CSF1R Protein, Human, Recombinant (mFc) | Human | HEK293 |
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein... | |||
TMPY-00816 | GM-CSFR alpha Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification... | |||
TMPY-04829 | G-CSF Protein, Human, Recombinant | Human | HEK293 |
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial... | |||
TMPY-00464 | M-CSF/CSF1 Protein, Mouse, Recombinant | Mouse | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-05636 | G-CSF Protein, Mouse, Recombinant | Mouse | HEK293 |
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial... | |||
TMPJ-00327 | M-CSF/CSF1 Protein, Human, Recombinant (His) | Human | Human Cells |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th... | |||
TMPY-01871 | IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) | Human | HEK293 |
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept... | |||
TMPY-01280 | FOLR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ... | |||
TMPY-01650 | CD131 Protein, Human, Recombinant (His) | Human | HEK293 |
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt... | |||
TMPY-00637 | FLT1 Protein, Human, Recombinant (aa 1-328, His) | Human | HEK293 |
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si... | |||
TMPY-01845 | IL-10 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-05064 | IL-10 Protein, Mouse, Recombinant | Mouse | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-03547 | IL-10 Protein, Human, Recombinant | Human | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-00127 | M-CSF/CSF1 Protein, Human, Recombinant | Human | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-05181 | M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-04229 | M-CSF/CSF1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-00813 | G-CSF Protein, Human, Recombinant (hFc) | Human | HEK293 |
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial... | |||
TMPY-05335 | M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-03537 | M-CSF/CSF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-04705 | M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPY-04704 | M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc) | Cynomolgus,Rhesus | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPK-01325 | M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of... | |||
TMPJ-00091 | G-CSF Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis ... | |||
TMPK-00322 | M-CSF/CSF1 Protein, Human, Recombinant (aa 33-190) | Human | HEK293 |
CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of... | |||
TMPY-04283 | CD131 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt... | |||
TMPK-00416 | FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | CHO |
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the re... | |||
TMPY-03109 | PHYH Protein, Human, Recombinant | Human | E. coli |
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and ... | |||
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