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1744
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14847 | B I09 | Others , IRE1 | |
B I09, an IRE-1 RNase inhibitor with an IC50 of 1230 nM, inhibits splicing of XBP1 mRNA in human WaC3 cells and expression of xbp-1 in LPS-stimulated B cells. B I09 can be used to simulate the defects of XBP-1 in CLL cel... | |||
T16157 | MT-802 | BTK , PROTACs | |
MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL). | |||
T10483 | Lisaftoclax | Bcl-2/Bcl-xl inhibitor 1,APG-2575 | BCL |
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL... | |||
T76909 | Apolizumab | ||
Apolizumab (Hu1D10), a humanized monoclonal antibody targeting the Human leukocyte antigen-DR beta-chain, has been shown to induce apoptosis in chronic lymphocytic leukemia (CLL) cells in vitro [1] [2]. | |||
T76729 | Lucatumumab | ||
Lucatumumab (HCD122), a fully human anti-CD40 antagonist monoclonal antibody, effectively inhibits CD40/CD40L-mediated signaling and promotes antibody-dependent cell-mediated cytotoxicity (ADCC) for tumor cell clearance.... | |||
T72527 | Umbralisib sulfate | TGR-1202 sulfate ; RP-5264 sulfate,TGR-1202 sulfate,RP-5264 sulfate | |
Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates u... | |||
T72465 | Umbralisib tosylate | RP5264 tosylate,TGR-1202 tosylate ; RP5264 tosylate,TGR-1202 tosylate | |
Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02092 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41~45 kDa and the accession number is EAW96132.1. | |||
TMPY-06865 | CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.12 kDa and the accession number is NP_808354.1. | |||
TMPK-00548 | CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPK-01002 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPK-01004 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc) | Human | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPK-01003 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated | Human | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPK-01005 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled | Human | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPY-06866 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.38 kDa and the accession number is EAW96132.1. | |||
TMPK-00995 | CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His) | Mouse | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPK-01006 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) | Human | HEK293 Cells |
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b... | |||
TMPY-06881 | CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated | Human | HEK293 Cells |
CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is 51.61 kDa and the accession number is EAW96132.1. | |||
TMPJ-01386 | STUB1 Protein, Human, Recombinant | Human | E. coli |
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03958 | TGF alpha Protein, Human, Recombinant | Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared... | |||
TMPY-04069 | Neurotrophin 3 Protein, Human, Recombinant | Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate... | |||
TMPY-02907 | FGF-19 Protein, Human, Recombinant | Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu... | |||
TMPK-00383 | ACE2/ACEH Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPY-02019 | CD59 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1. | |||
TMPY-01461 | EMAP-II/AIMP1 Protein, Human, Recombinant (His) | Human | E. coli |
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1. | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-01912 | Cadherin 17/CDH17 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1. | |||
TMPY-02031 | B7-H3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-02525 | RGMA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th... | |||
TMPY-04262 | B7-H3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-00915 | Serpin A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. | |||
TMPY-02836 | MFGE8 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1. | |||
TMPY-01462 | IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1. | |||
TMPK-00176 | BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (... | |||
TMPY-02034 | Siglec-2/CD22 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPY-02794 | TLR2 Protein, Human, Recombinant (aa 1-587, His) | Human | Baculovirus Insect Cells |
TLR2 Protein, Human, Recombinant (aa 1-587, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 65.5 kDa and the accession number is O60603-1. | |||
TMPY-04799 | IFNAR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPY-02647 | IFNAR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1. | |||
TMPY-04826 | LILRB5/CD85c Protein, Human, Recombinant (His) | Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le... | |||
TMPY-00740 | SDF-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SDF-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P48061-1. | |||
TMPY-04698 | HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is P04626-1. | |||
TMPY-00203 | LOXL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ... | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. | |||
TMPY-01023 | CD38 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD38 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P28907-1. | |||
TMPK-01074 | CD163 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.8 kDa and the accession number is P06332-1. | |||
TMPY-01305 | OSMR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
OSMR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.6 kDa and the accession number is Q99650-1. | |||
TMPY-04753 | IRE1 Protein, Human, Recombinant (aa 465-977) | Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1. | |||
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