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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2331 | Solithromycin | OP-1068,CEM-101 | Antibacterial , Antibiotic |
Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop... | |||
T39810 | CEM114 | ||
CEM114 is a potent chemical compound known as a chemical epigenetic modifier (CEM). It functions by employing CRISPR-Cas9 systems to harness endogenous chromatin machinery, thereby exerting its epigenetic modifying effec... | |||
T9104 | TJ191 | Apoptosis | |
TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. | |||
T20038 | 2-Fluoroadenine | NSC-27364,NSC 27364,NSC27364 | DNA/RNA Synthesis |
2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies. | |||
T6018 | Zosuquidar trihydrochloride | Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride | P-gp |
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T5858 | Sertindole | Lu 23-174 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy |
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively) | |||
T16731 | Rentiapril racemate | (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril | Angiotensin-converting Enzyme (ACE) |
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research. | |||
T13514 | 5-MethoxyPinocembroside | Others | |
5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera. | |||
T4345 | CeMMEC1 | CeMMEC1 HCl | Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis |
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM). | |||
T7220 | Prohydrojasmon racemate | Propyl dihydrojasmonate,Prohydrojasmon | Others |
Prohydrojasmon racemate (Propyl dihydrojasmonate) is a synthesized plant gowth regulator, which has jasmonic acid activity. | |||
T50055 | Milacemide | MAO | |
Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease. | |||
T20700 | Racemetirosine | Others | |
Racemetirosine is an inhibitor of Tyrosine 3-monooxygenase, and consequently it inhibits the synthesis of catecholamines. | |||
T13331 | WAY127093B racemate | PDE | |
WAY127093B racemate is the racemate of WAY127093B. WAY127093B is a phosphodiesterase IV inhibitor with oral activity in rats and guinea pigs. | |||
T22253 | AG-120 (racemic) | Dehydrogenase | |
AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic activity. | |||
T9005 | VPC-80051 racemate | Others | |
VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach. | |||
T22988 | MK-4827 Racemate | Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide | PARP |
MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1. | |||
TN1499 | Cimiracemoside C | Cimicifugoside M | AMPK |
Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes. | |||
T11178L | ELN318463 racemate | ELN318463 (racemate),ELN 318463 racemate | Gamma-secretase |
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor. | |||
T6809 | CPI-169 racemate | CPI 169,CPI-169,CPI169 | Epigenetic Reader Domain , Histone Methyltransferase |
CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively. |