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AG-120 (racemic)

Catalog No. T22253 CAS 1448346-63-1

AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate Dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic activity.

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AG-120 (racemic), CAS 1448346-63-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 47.00
2 mg	In stock	$ 65.00
5 mg	In stock	$ 94.00
10 mg	In stock	$ 141.00
25 mg	In stock	$ 280.00
50 mg	In stock	$ 412.00
100 mg	In stock	$ 613.00
1 mL * 10 mM (in DMSO)	In stock	$ 148.00

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Purity: 98.99%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic activity.

Molecular Weight	582.96
Formula	C28H22ClF3N6O3
CAS No.	1448346-63-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 50 mg/mL (85.77 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related compound libraries

This product is contained In the following compound libraries：

Immunology/Inflammation Compound Library Bioactive Compound Library Approved Drug Library Orally Active Compound Library Metabolism Compound Library Clinical Compound Library Anti-Cancer Metabolism Compound Library Drug Repurposing Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library

Related Products

Related compounds with same targets

11β-HSD1-IN-1 DSM421 ALDH1A3-IN-2 CB29 1-(biphenyl-4-ylsulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine ALDH2 modulator 1 AGI-14100 DHODH-IN-17

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AG-120 (racemic) 1448346-63-1 Metabolism Dehydrogenase AG 120 (racemic) AG120 (racemic) inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.