as-19 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10380	AS19		5-HT Receptor
	AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively).		5-HT Receptor
T12205	Ned 19		Calcium Channel
	Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice.		Calcium Channel
TP1053L	Protein Kinase C 19-31 acetate	Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate	PKC
	Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is...		PKC
T60095	CCF0058981		SARS-CoV
	CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-...		SARS-CoV
T76781	Itolizumab	EQ-001	Others
	Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti...		Others
T14366	AZ10606120 dihydrochloride		P2X Receptor
	AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and ...		P2X Receptor
T60165	VB124		Monocarboxylate transporter
	VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cell...		Monocarboxylate transporter
TN3651	Cichoriin		Others
	Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.		Others
T9287	Hydroxychloroquine	2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol	SARS-CoV , TLR , Parasite , Autophagy
	Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It i...		SARS-CoV , TLR , Parasite , Autophagy
T67747	CB2R/FAAH modulator-3		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ...		Cannabinoid Receptor , FAAH
T8070	Nonadecanoic acid		Others
	Nonadecanoic acid is a long saturated fatty acid found in ox fats and vegetable oils, and in Staphylococcus. It can be used as a phermone by certain insects.		Others
T0134	Imiquimod	R 837,S-26308	SARS-CoV , TLR , Autophagy , HSV
	Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.		SARS-CoV , TLR , Autophagy , HSV
T67745	CB2R/FAAH modulator-2		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an...		Cannabinoid Receptor , FAAH
T0194	Chloroquine phosphate	Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T3921	Punicalagin		SARS-CoV , HBV
	Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula...		SARS-CoV , HBV
T0825	Ebselen	SPI-1005,PZ-51,CCG-39161	Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
	Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T39581	PI3K-IN-19 hydrochloride	PI3K-IN-19 hydrochloride
	PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor.
T81083	STING agonist-19
	STING agonist-19 serves as a precursor for the synthesis of immune-stimulating antibody conjugates (ISACs).
T82166	HSP90-IN-27		HSP
	HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].		HSP
T81732	Myosin light chain kinase fragment 11-19 amide	MLCK(11-19) amide
	Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) serves both as a substrate-specific peptide inhibitor of MLCK and as an inhibitor of hypotonicity-induced Ca2+ entry. This compound has applications in t...