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Search Results for " γ(c) "

23

Compounds

8

Natural Products

26

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76419 Protein Kinase C γ Peptide
Protein Kinase C (gamma) Peptide, a fragment of Protein Kinase Cγ, plays a role in dominant ataxia by inhibiting the nuclear import of aprataxin, which is associated with recessive ataxia [1].
T15212 Emamectin Benzoate MK-244 Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T10115 3-Nitrocoumarin 3-nitrochromen-2-one Phospholipase
3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.
T14903 CCT129957 Calcium Channel , Phospholipase
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
T33519 MTOB α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid Others
MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...
T1706 4-Hydroxy-3-nitrophenylacetic acid Others
4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.
T3689 Ruboxistaurin hydrochloride Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride PKC
Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...
T7621 6-​Thioinosine 6-Mercaptopurine riboside,6TI Nucleoside Antimetabolite/Analog
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.
T10549 Bisindolylmaleimide VIII acetate Ro 31-7549 acetate,Bis VIII acetate Apoptosis , PKC
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, resp...
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...
T26019 R59949 R-59949,R 59949 Others , PKC
R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.
T62726 Phenylpyropene C
Phenylpyropene C (S14-95) is a JAK/STAT pathway inhibitor that exhibits inhibition of IFN-γ-mediated reporter gene expression (IC50: 5.4-10.8 μM) and is also an inhibitor of acyl coenzyme A (IC50: 16.0 μM).
T35971 4-hydroxy Nonenal Mercapturic Acid
Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as...
T75405 GlcNAc kinase (EcNagK)
N-Acetylglucosamine kinase (EcNagK), a key enzyme in GlcNAc metabolism, catalyzes the transfer of the gamma-phosphoryl group from ATP to the hydroxyl group at the C-6 position of GlcNAc, producing GlcNAc-6-P [1].
T68980 MRK003
MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. MRK003 treatment induced caspase-dependent apoptosis and inhibited proliferation of MM a...
T79487 MAO A/HSP90-IN-2 Monoamine Oxidase
MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90. This compound not only enhances HSP70 expression but also diminishes HER2 and phosph...
T37201 CAY10787
CAY10787 is an oxysterol and a negative allosteric modulator of GABAAreceptors.1,2It reduces GABA-induced currents in HEK cells expressing α1β1γ2or α4β3γ2subunit-containing GABAAreceptors (IC50s = 1.5 and 1 μM, respectiv...
T38356 1,2-Dipalmitoyl-13C-sn-glycero-3-PC
1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerop...
T37044 1,2-Dioleoyl-rac-glycerol-13C3 1,2-Dioleoyl-rac-glycerol-13C3
1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at th...
TP2212 A-MSH, amide Others
a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of pept...
T83485 [Thr28, Nle31]-Cholecystokinin (25-33), sulfated
[Thr28, Nle31]-Cholecystokinin (25-33) is a bioactive peptide analog of Cholecystokinin (CCK), functioning as both a hormone and neurotransmitter within the gastrointestinal system and central nervous system, with a role...
T80249 Epsilon-V1-2, Cys-conjugated PKC
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...
T36486 Benpyrine
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten...

Compounds

Protein Kinase C γ Peptide
T76419
Synonym:
Target:
Emamectin Benzoate
T15212
Synonym: MK-244
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite
3-Nitrocoumarin
T10115
Synonym: 3-nitrochromen-2-one
Target: Phospholipase
CCT129957
T14903
Synonym:
Target: Calcium Channel, Phospholipase
MTOB
T33519
Synonym: α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid
Target: Others
4-Hydroxy-3-nitrophenylacetic acid
T1706
Synonym:
Target: Others
Ruboxistaurin hydrochloride
T3689
Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride
Target: PKC
6-​Thioinosine
T7621
Synonym: 6-Mercaptopurine riboside,6TI
Target: Nucleoside Antimetabolite/Analog
Bisindolylmaleimide VIII acetate
T10549
Synonym: Ro 31-7549 acetate,Bis VIII acetate
Target: Apoptosis, PKC
Midostaurin
T3211
Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251
Target: Others, PKC
R59949
T26019
Synonym: R-59949,R 59949
Target: Others, PKC
Phenylpyropene C
T62726
Synonym:
Target:
4-hydroxy Nonenal Mercapturic Acid
T35971
Synonym:
Target:
GlcNAc kinase (EcNagK)
T75405
Synonym:
Target:
MRK003
T68980
Synonym:
Target:
MAO A/HSP90-IN-2
T79487
Synonym:
Target: Monoamine Oxidase
CAY10787
T37201
Synonym:
Target:
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
T38356
Synonym:
Target:
1,2-Dioleoyl-rac-glycerol-13C3
T37044
Synonym: 1,2-Dioleoyl-rac-glycerol-13C3
Target:
a-MSH, amide
TP2212
Synonym:
Target: Others
[Thr28, Nle31]-Cholecystokinin (25-33), sulfated
T83485
Synonym:
Target:
Epsilon-V1-2, Cys-conjugated
T80249
Synonym:
Target: PKC
Benpyrine
T36486
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T20682 γ-Cyclodextrin Gamma cyclodextrin,Ringdex C,gamma-Dextrin,Cyclooctaamylose Endogenous Metabolite
γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.
T3417 Amentoflavone Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T4719 1,4-D-Gulonolactone D-Gulonic acid γ-lactone Others , Endogenous Metabolite
1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis...
T5578 L-Gulono-1,4-lactone Others , Endogenous Metabolite
L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C.
T3867 Alpinetin (-)-alpinetin BCL , PPAR
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he...
T3824 Jaceosidin Apoptosis , BCL , COX , UGT
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...
T35895 Ingenol 3,20-dibenzoate
Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the partic...
T75611 Tibesaikosaponin V
Tibesaikosaponin V (TKV), a triterpene diglycoside isolated from the methanol extract of Bupleurum chinense DC roots, effectively inhibits lipid accumulation and triacylglycerol content in adipocytes without inducing cyt...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00857 IL-2RG Protein, Mouse, Recombinant (His & hFc) Mouse HEK293 Cells
IL-2RG Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.3 kDa and the accession number is P34902.
TMPY-01837 IL-2RG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
IL-2RG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P34902.
TMPY-06507 IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc) Mouse HEK293 Cells
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is NP_038591.1.
TMPY-04703 GRO gama/CXCL3 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
GRO gama/CXCL3 Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.3 kDa and the accession number is Q6W5C0.
TMPY-03794 CEBP gamma Protein, Human, Recombinant (His) Human E. coli
CEBPG, also known as CEBP gamma, is a transcription factor which belongs to the CEBP family. Members of this family regulate viral and cellular CCAAT/enhancer element-mediated transcription. CEBP proteins contain the bZI...
TMPJ-00893 IgG2a Protein, Rat, Recombinant Rat HEK293 Cells
Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG...
TMPJ-00751 IgG4 hFc Protein, Human, Recombinant (aa 99-326) Human HEK293 Cells
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-00750 IgG1 hFc Protein, Human, Recombinant, Biotinylated Human HEK293 Cells
IgG1 hFc Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 33 KDa and the accession number is P01857.
TMPJ-00749 IgG1 hFc Protein, Human, Recombinant Human HEK293 Cells
IgG1 hFc Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32 KDa and the accession number is P01857.
TMPJ-00597 IgG1 hFc Protein, Mouse, Recombinant Mouse HEK293 Cells
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ...
TMPJ-00027 CST3 Protein, Human, Recombinant (Mammalian) Human HEK293 Cells
CST3 Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15 KDa and the accession number is P01034.
TMPJ-00884 CXCL9 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun...
TMPJ-00008 CXCL10 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPJ-00900 TGM2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monom...
TMPJ-01084 CXCL9 Protein, Human, Recombinant (His) Human HEK293 Cells
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPY-00899 GRO gama/CXCL3 Protein, Human, Recombinant (His) Human E. coli
GRO gama/CXCL3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P19876.
TMPJ-01000 CCL9 Protein, Mouse, Recombinant Mouse E. coli
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some express...
TMPK-00317 IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00512 IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) Cynomolgus HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00316 IL-18R alpha Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPJ-00072 IL-18BPd Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPY-02519 BLVRB Protein, Human, Recombinant (His) Human E. coli
Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPJ-00446 CD32A Protein, Human, Recombinant (R167, His) Human HEK293 Cells
Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (C...
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
IL-2RG Protein, Mouse, Recombinant (His & hFc)
TMPY-00857
Species: Mouse
Expression System: HEK293 Cells
IL-2RG Protein, Mouse, Recombinant (His)
TMPY-01837
Species: Mouse
Expression System: HEK293 Cells
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc)
TMPY-06507
Species: Mouse
Expression System: HEK293 Cells
GRO gama/CXCL3 Protein, Mouse, Recombinant (His)
TMPY-04703
Species: Mouse
Expression System: P. pastoris (Yeast)
CEBP gamma Protein, Human, Recombinant (His)
TMPY-03794
Species: Human
Expression System: E. coli
IgG2a Protein, Rat, Recombinant
TMPJ-00893
Species: Rat
Expression System: HEK293 Cells
IgG4 hFc Protein, Human, Recombinant (aa 99-326)
TMPJ-00751
Species: Human
Expression System: HEK293 Cells
IgG1 hFc Protein, Human, Recombinant, Biotinylated
TMPJ-00750
Species: Human
Expression System: HEK293 Cells
IgG1 hFc Protein, Human, Recombinant
TMPJ-00749
Species: Human
Expression System: HEK293 Cells
IgG1 hFc Protein, Mouse, Recombinant
TMPJ-00597
Species: Mouse
Expression System: HEK293 Cells
CST3 Protein, Human, Recombinant (Mammalian)
TMPJ-00027
Species: Human
Expression System: HEK293 Cells
CXCL9 Protein, Mouse, Recombinant (His)
TMPJ-00884
Species: Mouse
Expression System: HEK293 Cells
CXCL10 Protein, Human, Recombinant (hFc & His)
TMPJ-00008
Species: Human
Expression System: HEK293 Cells
TGM2 Protein, Mouse, Recombinant (His)
TMPJ-00900
Species: Mouse
Expression System: HEK293 Cells
CXCL9 Protein, Human, Recombinant (His)
TMPJ-01084
Species: Human
Expression System: HEK293 Cells
GRO gama/CXCL3 Protein, Human, Recombinant (His)
TMPY-00899
Species: Human
Expression System: E. coli
CCL9 Protein, Mouse, Recombinant
TMPJ-01000
Species: Mouse
Expression System: E. coli
IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00317
Species: Human
Expression System: HEK293 Cells
IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
TMPK-00512
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18R alpha Protein, Human, Recombinant (His & Avi)
TMPK-00316
Species: Human
Expression System: HEK293 Cells
IL-18BPd Protein, Mouse, Recombinant (hFc)
TMPJ-00072
Species: Mouse
Expression System: HEK293 Cells
BLVRB Protein, Human, Recombinant (His)
TMPY-02519
Species: Human
Expression System: E. coli
CD32A Protein, Human, Recombinant (R167, His)
TMPJ-00446
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01456
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01450
Species: Human
Expression System: HEK293 Cells
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01451
Species: Human
Expression System: HEK293 Cells
TargetMol