store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 108.00 | |
10 mg | In stock | $ 158.00 | |
25 mg | In stock | $ 266.00 | |
50 mg | In stock | $ 395.00 | |
100 mg | In stock | $ 587.00 | |
500 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells. |
Targets&IC50 | PLCγ:3 μM |
In vitro | The left phenyl group is situated within a hydrophobic pocket formed by various amino acids. The predicted binding mode of CCT129957 exhibits a robust hydrogen bonding pattern and hydrophobic contacts[1].CCT129957 inhibits the growth of renal UO-31 and breast T-47D cancer cells by approximately 60-70%[2]. |
Molecular Weight | 309.32 |
Formula | C17H15N3O3 |
CAS No. | 883098-58-6 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (161.64 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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CCT129957 883098-58-6 Membrane transporter/Ion channel Metabolism Calcium Channel Phospholipase CCT 129957 CCT-129957 inhibitor inhibit