onset — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38612	Linaprazan glurate		Others
	Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases.		Others
T0802	Procaine hydrochloride	Novocaine HCl,Procaine HCl	Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR
	Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel...
T0029	Procaine	Duracaine,Spinocaine,Novocaine,Vitamin H3	Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
	Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.		Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
T7806	Licarbazepine	10,11-hydroxy-10,11 Dihydrocarbamezer	Others
	Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.		Others
T80855	Vonsetamig
	Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.
T19564	Stearoylcarnitine	Stearoyl-L-carnitine	Endogenous Metabolite
	Stearoylcarnitine (Stearoyl-L-carnitine) is a fatty ester lipid molecule, a human endogenous metabolite that serves as a biomarker for early-onset preeclampsia and late-onset preeclampsia.		Endogenous Metabolite
T3285L	Eslicarbazepine	Pazzul,EC 810-248-9,BIA 2-194,Stedesa,Erelib	Beta-Secretase , Sodium Channel
	Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.		Beta-Secretase , Sodium Channel
T24932	Vatanidipine	AE-0047,AE 0047,AE0047	Calcium Channel
	Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensi...		Calcium Channel
T31860	Fosdevirine	GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A	HIV Protease
	Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.		HIV Protease
T31716L	Etidocaine		Others
	Etidocaine is an amino acidamide that acts as a local anesthetic with fast onset and long-acting properties.		Others
T3285	Eslicarbazepine Acetate	Zebinix,Aptiom,BIA 2-093,Exalief,Stedesa	Beta-Secretase , Sodium Channel
	Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conve...		Beta-Secretase , Sodium Channel
T1148	Menbutone	Naftobil,Genabilic acid,Genabilin	Others
	Menbutone (Genabilin) is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.		Others
T9284	Dexketoprofen trometamol		COX
	Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations.		COX
T7502L	PF 05089771	PF-05089771,PF05089771	Sodium Channel
	PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.		Sodium Channel
T7942	Tranylcypromine hemisulfate	Tranylcypromine Sulfate,Tranylcypromine (hemisulfate)	Histone Demethylase , MAO , Monoamine Oxidase
	Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.		Histone Demethylase , MAO , Monoamine Oxidase
T4250	Bilastine	Bilaxten	Histamine Receptor
	Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.		Histamine Receptor
TP1127L1	Nemifitide acetate(173240-15-8 free base)	INN 00835 acetate	5-HT Receptor
	Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).		5-HT Receptor
T9299	D-Leucine	(R)-Leucine	Endogenous Metabolite
	D-Leucine ((R)-Leucine) potently terminates seizures even after the onset of seizure activity. D-leucine reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.		Endogenous Metabolite
T31860L	(Iso)-Fosdevirine	(Iso)-Fosdevirine（Iso-1018450-26-4）,(Iso)-GSK2248761	HIV Protease
	(Iso)-Fosdevirine ( (Iso)-GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological disorders such as late-onset epilepsy.		HIV Protease
T1439	Lacidipine	SN-305,GX-1048,GR-43659X	Apoptosis , Calcium Channel , Reactive Oxygen Species
	Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi...		Apoptosis , Calcium Channel , Reactive Oxygen Species