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Eslicarbazepine

Catalog No. T3285L   CAS 104746-04-5
Synonyms: Pazzul, EC 810-248-9, BIA 2-194, Stedesa, Erelib

Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.

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Eslicarbazepine Chemical Structure
Eslicarbazepine, CAS 104746-04-5
Pack Size Availability Price/USD Quantity
5 mg In stock $ 47.00
10 mg In stock $ 80.00
25 mg In stock $ 155.00
50 mg In stock $ 239.00
100 mg In stock $ 372.00
200 mg In stock $ 549.00
1 mL * 10 mM (in DMSO) In stock $ 52.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.
In vitro Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].
Synonyms Pazzul, EC 810-248-9, BIA 2-194, Stedesa, Erelib
Molecular Weight 254.28
Formula C15H14N2O2
CAS No. 104746-04-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12 mg/mL (47.19 mM)

TargetMolReferences and Literature

1. Doeser A, Soares-da-Silva P, Beck H, Uebachs M. The effects of eslicarbazepine on persistent Na⁺ current and the role of the Na⁺ channel β subunits. Epilepsy Res. 2014 Feb;108(2):202-11. doi: 10.1016/j.eplepsyres.2013.11.022. Epub 2013 Dec 8. PubMed PMID: 24368131. 2. Keating GM. Eslicarbazepine acetate: a review of its use as adjunctive therapy in refractory partial-onset seizures. CNS Drugs. 2014 Jul;28(7):583-600. doi: 10.1007/s40263-014-0182-2. Review. PubMed PMID: 24972948. 3. Verrotti A, Loiacono G, Rossi A, Zaccara G. Eslicarbazepine acetate: an update on efficacy and safety in epilepsy. Epilepsy Res. 2014 Jan;108(1):1-10. doi: 10.1016/j.eplepsyres.2013.10.005. Epub 2013 Oct 23. Review. PubMed PMID: 24225327. 4. Elger C, Bialer M, Falcão A, Vaz-da-Silva M, Nunes T, Almeida L, Soares-da-Silva P. Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers. Epilepsia. 2013 Aug;54(8):1453-61. doi: 10.1111/epi.12242. Epub 2013 Jun 12. PubMed PMID: 23758485.

Related compound libraries

This product is contained In the following compound libraries:
Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Approved Drug Library Orally Active Compound Library Clinical Compound Library Bioactive Compound Library

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Keywords

Eslicarbazepine 104746-04-5 Membrane transporter/Ion channel Neuroscience Sodium Channel Beta-Secretase Pazzul Inhibitor EC 810-248-9 inhibit BIA 2-194 Stedesa Erelib inhibitor

 

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