Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 48.00 |
Description | Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity. |
In vivo | Tranylcypromine-induced transcriptional and epigenetic regulation modulated RGC survival via the promotion of p38 MAPKγ activity. Therefore, pharmacologic treatments that suppress LSD1 activity may be a novel therapeutic strategy that can be used to treat neurodegenerative diseases[1]. |
Animal Research | The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1]. |
Synonyms | Tranylcypromine Sulfate, Tranylcypromine (hemisulfate) |
Molecular Weight | 182.23 |
Formula | C9H11N 1/2H2SO4 |
CAS No. | 13492-01-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mg/mL (54.8 mM), Sonification is recommended
DMSO: 3.33 mg/mL (18 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tranylcypromine hemisulfate 13492-01-8 Chromatin/Epigenetic Metabolism Neuroscience MAO Histone Demethylase Monoamine Oxidase dl-Tranylcypromine hemisulfate Tranylcypromine Tranylcypromine Hemisulfate inhibit Tranylcypromine Sulfate Inhibitor Tranylcypromine (hemisulfate) inhibitor