Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity.
Description | Tranylcypromine is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity. |
In vivo | Tranylcypromine-induced transcriptional and epigenetic regulation modulated RGC survival via the promotion of p38 MAPKγ activity. Therefore, pharmacologic treatments that suppress LSD1 activity may be a novel therapeutic strategy that can be used to treat neurodegenerative diseases[1]. |
Animal Research | The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1]. |
Synonyms | Tranylcypromine (hemisulfate), Tranylcypromine Sulfate, 反苯环丙胺半硫酸盐 |
Molecular Weight | 364.46 |
Formula | C18H24N2O4S |
CAS No. | 13492-01-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 5 mg/mL (27.44 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Tranylcypromine hemisulfate 13492-01-8 表观遗传 代谢 神经科学 Histone Demethylase MAO Monoamine Oxidase Tranylcypromine Sulfate dl-Tranylcypromine hemisulfate Tranylcypromine (hemisulfate) inhibit Inhibitor inhibitor