non-competitive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8580	Bupranolol		Adrenergic Receptor
	Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.		Adrenergic Receptor
T8459	DNQX disodium salt	DNQX Disodium	NMDAR , iGluR
	DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor		NMDAR , iGluR
T7304	DNQX	FG 9041	GluR , iGluR
	DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)		GluR , iGluR
T1817	GNF-2	GNF2	SARS-CoV , Bcr-Abl
	GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.		SARS-CoV , Bcr-Abl
T23524	W-84 dibromide	HDMPPA	AChR
	W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.		AChR
T6223	U0126-EtOH	U0126 Ethanol,U0126	Mitophagy , Influenza Virus , MEK , Autophagy
	U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).		Mitophagy , Influenza Virus , MEK , Autophagy
T6893	MK-886	MK886,L 663536	Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
	MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.		Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
T10898	Samuraciclib hydrochloride	ICEC0942 hydrochloride,CT7001 hydrochloride	Apoptosis , CDK
	Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold h...		Apoptosis , CDK
T10774	CFM-2		iGluR
	CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.		iGluR
TP2058L	Catestatin acetate	Catestatin acetate(142211-96-9 free base)	Endogenous Metabolite , AChR
	Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure.		Endogenous Metabolite , AChR
T26645	Aptiganel	CNS 1102,CNS-1102,CNS1102	NMDAR
	Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke.		NMDAR
T2362	QNZ46		NMDAR , iGluR
	QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.		NMDAR , iGluR
T22692	CPCCOEt		GluR
	CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b		GluR
T23588	9-CP-Ade Mesylate	9-Cyclopentyladenine monomethanesulfonate,9 CP Ade Mesylate,9CPAde Mesylate	AChR
	9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.		AChR
T11054	DL-Norvaline	2-Aminopentanoic acid	Arginase , Endogenous Metabolite
	DL-Norvaline (2-Aminopentanoic acid) is a non-competitive inhibitor of arginase.		Arginase , Endogenous Metabolite
T3419	Chelerythrine chloride		Apoptosis , BCL , PKC , Autophagy
	Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.		Apoptosis , BCL , PKC , Autophagy
T8685	SP-146		Aurora Kinase
	SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).		Aurora Kinase
T23048	N20C hydrochloride	2-((3,3-diphenylpropyl)amino)acetamide hydrochloride	NMDAR
	N20C hydrochloride (2-((3,3-diphenylpropyl)amino)acetamide hydrochloride) is a non-competitive NMDA receptor open-channel blocker.		NMDAR
T14988	CMPD1		MAPK
	CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).		MAPK
T5053	Eprobemide	LIS 630	MAO , Monoamine Oxidase
	Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).		MAO , Monoamine Oxidase