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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0042 | Xylometazoline hydrochloride | Xylometazoline HCl | Adrenergic Receptor |
Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant. | |||
T38236 | 2′-Deoxy-2′-fluoroguanosine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... | |||
T4S0878 | Prunetin | Prunusetin | ERK , Dehydrogenase , NF-κB |
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit... | |||
T4563 | Thonzylamine | neohetramine | Histamine Receptor |
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... | |||
T0397 | Tetrahydrozoline | Tetryzolin,Tetryzoline | Adrenergic Receptor |
Tetrahydrozoline (Tetryzoline), an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular irritants. | |||
T22033 | ARC 239 dihydrochloride | Norepinephrine | |
ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively). | |||
T6703 | Tetrahydrozoline hydrochloride | Murine Plus,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl | Adrenergic Receptor |
Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity. | |||
T0335 | Sodium salicylate | Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt | Apoptosis , NF-κB , COX , S6 Kinase , Autophagy |
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress. | |||
T26009 | Quazolast | RHC-3988,RHC 3988,RHC3988 | Others |
Quazolast (RHC 3988) is a potent mediator release inhibitor and is a control against ragweed antigenic nasal challenge. quazolast is superior to placebo in preventing nasal congestion and nasal itching following ragweed ... | |||
T71012 | Nemazoline Free Base | ||
Nemazoline Free Base is a nasal decongestant. It has alpha 1-agonist/alpha 2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo. Upon intranasal adm... | |||
T3612 | Carbocisteine | Carbocysteine,Broncodeterge,Mucodyne,S-Carboxymethyl-L-cysteine | Others |
Carbocisteine (Mucodyne) is commonly used as an anti-infective nasal spray with mucolytic and expectorant effects. | |||
TN1610 | Epimagnolin A | Parasite | |
Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion. | |||
T0113 | Mebhydrolin napadisylate | Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline | 5-HT Receptor , AChR , Histamine Receptor |
Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. | |||
T1287 | Synephrine | Oxedrine | Endogenous Metabolite , Adrenergic Receptor |
Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma. | |||
T4764 | 5-Methoxy-5-oxopentanoic acid | mono-Methyl glutarate,METHYL HYDROGEN GLUTARATE | Others , Endogenous Metabolite |
5-Methoxy-5-oxopentanoic acid (mono-Methyl glutarate) is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monomethyl esters (... | |||
T21404 | Fluticasone furoate | Veramyst,Allermist,Avamys,Fluticasone furoate | Glucocorticoid Receptor |
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... | |||
T21390 | Fexofenadine | Carboxyterfenadine,Telfast,MDL 16.455,Allegra | Histamine Receptor |
Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is... | |||
T35455 | N-Nitrosodiethylamine | Diethylnitrosamine,NDEA | DNA/RNA Synthesis |
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso... | |||
T0900 | Cetylpyridinium chloride monohydrate | Hexadecylpyridinium chloride monohydrate | Antibacterial , Antibiotic |
Cetylpyridinium chloride monohydrate (Hexadecylpyridinium chloride monohydrate) , a cationic quaternary ammonium compound, is used in certain classes of throat sprays, mouthwashes, lozenges, toothpaste, nasal sprays, and... | |||
T69341 | Tramazoline hydrochloride | ||
Tramazoline hydrochloride is commonly used in nasal spray as a nasal decongestant by acting as an α-adrenergic receptor agonist that inhibits secretion of nasal mucus. |