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Synephrine

Catalog No. T1287   CAS 94-07-5
Synonyms: Oxedrine

Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.

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Synephrine Chemical Structure
Synephrine, CAS 94-07-5
Pack Size Availability Price/USD Quantity
10 mg In stock $ 40.00
25 mg In stock $ 63.00
50 mg In stock $ 81.00
100 mg In stock $ 113.00
500 mg In stock $ 273.00
1 mL * 10 mM (in DMSO) In stock $ 45.00
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Purity: 100%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
In vitro Synephrine is a compound commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. [1] [2] Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells. [3]
In vivo LD50: Mice >1000 mg/kg (s.c.) [4]
Source
Synonyms Oxedrine
Molecular Weight 167.21
Formula C9H13NO2
CAS No. 94-07-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 2 mg/mL (11.96 mM), warmed

DMSO: 31 mg/mL (185.4 mM)

TargetMolReferences and Literature

1. Stohs SJ, et al. Int J Med Sci, 2012, 9(7), 527-538. 2. Haaz S, et al. Obes Rev, 2006, 7(1), 79-88. 3. Hong NY, et al. Biochem Biophys Res Commun, 2012, 418(4), 720-724. 4. Unna K, et al. Archivfuer Experimentelle Pathologie und Pharmakologie, 1951, 213, 207-234.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Compound Library Neuronal Signaling Compound Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compound Library ReFRAME Related Library Human Endogenous Metabolite Compound Library Plus Natural Product Library

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Keywords

Synephrine 94-07-5 GPCR/G Protein Metabolism Neuroscience Adrenergic Receptor Endogenous Metabolite β-adrenergic inhibit alkaloid sympathomimetic Inhibitor weight Beta Receptor loss Oxedrine α-adrenergic inhibitor

 

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