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Xylometazoline hydrochloride

Catalog No. T0042 CAS 1218-35-5

Synonyms: Xylometazoline HCl

Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.

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Xylometazoline hydrochloride Chemical Structure

Xylometazoline hydrochloride, CAS 1218-35-5

Pack Size	Availability	Price/USD
500 mg	In stock	$ 46.00
1 g	In stock	$ 79.00
1 mL * 10 mM (in DMSO)	In stock	$ 51.00

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Purity: 100%

Purity: 99.83%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.
Targets&IC50	α1D-adrenoceptor:450 nM, α2C-adrenoceptor:220 nM, α2A-adrenoceptor:980 nM, α1A-adrenoceptor:80 nM, α1B-adrenoceptor:560 nM
In vitro	Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. Xylometazoline binds at adrenoceptor subtypeα1A, α1B, α1D, α2A, α2B, α2C with IC50 of 0.08, 0.56, 0.45, 0.98, 1.8, 0.22 μM, repectively. [1]

Synonyms	Xylometazoline HCl
Molecular Weight	280.84
Formula	C16H24N2·HCl
CAS No.	1218-35-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 26 mg/mL (92.6 mM)

Ethanol: 52 mg/mL (185.2 mM)

H2O: 51 mg/mL (181.6 mM)

References and Literature

1. Haenisch B, Fundam Clin Pharmacol, 2010, 24(6), 729-739.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library Anti-Cancer Drug Library Membrane Protein-targeted Compound Library Anti-Cancer Approved Drug Library GPCR Compound Library Anti-Cancer Compound Library NO PAINS Compound Library Anti-Obesity Compound Library

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Keywords

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