mechanism — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5399	GeA-69		PARP
	GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).		PARP
T14364	AZ-Dyrk1B-33	3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine	DYRK
	AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.		DYRK
T3817	Darutigenol		Others
	Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.		Others
T3S1319	(+)-Magnoflorine	Escholin,Magnoflorine,Thalictrin,Escholine	Others , Antifungal
	(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...		Others , Antifungal
T2320	Indacaterol		Adrenergic Receptor
	Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.		Adrenergic Receptor
T0990	Droperidol	NSC 169874,Dehydrobenzperidol	Dopamine Receptor
	Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.		Dopamine Receptor
T1096	Milrinone	Win 47203	PDE
	Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.		PDE
T1565	Deferiprone	Deferidone,CP20	Others , HCV Protease , Ferroptosis , UGT
	Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.		Others , HCV Protease , Ferroptosis , UGT
T21017	5'-Amino-5'-deoxyadenosine	5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis , Adenosine Receptor
	5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...		Apoptosis , Adenosine Receptor
TN7068	Sinomenine N-oxide		Others
	Sinomenine N-oxide is one of the major metabolites of the cyclic metabolic mechanism of Sinomenine.		Others
T3S0289	Araloside X		Calcium Channel
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox...		Calcium Channel
T4040	AN2718		Antifungal
	AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.		Antifungal
T0692	Allopurinol	Zyloric,Zyloprim,Lopurin	ROS , Xanthine Oxidase
	Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.		ROS , Xanthine Oxidase
T0142	Brinzolamide	AL-4862	Carbonic Anhydrase
	Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.		Carbonic Anhydrase
T2552	Succimer	DMSA,Dimercaptosuccinic acid,meso-2,3-dimercaptosuccinic acid	Others
	Succimer (Dimercaptosuccinic acid) is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.		Others
T3511	PF-1355	PF-06281355,PF 06281355,ZINC205721785	Glutathione Peroxidase
	PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.		Glutathione Peroxidase
T2411	Luliconazole	NND 502	Antibiotic , Antifungal
	Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.		Antibiotic , Antifungal
T1570	Telmisartan	BIBR 277	RAAS , Autophagy
	Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.		RAAS , Autophagy
T6S1894	Linderane		P450
	1. Linderane was characterized as a mechanism-based inactivator of CYP2C9.		P450
T4661	PKG drug G1		PKA
	PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.		PKA