Shopping Cart

Your shopping cart is currently empty

AN2718

Name: AN2718
Brand: TargetMol
SKU: T4040
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4040Cas No. 174672-06-1

AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.

AN2718

🥰Excellent

Purity: 98.89%

Catalog No. T4040Cas No. 174672-06-1

AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$43	In Stock	In Stock
10 mg	$61	In Stock	In Stock
25 mg	$97	In Stock	In Stock
50 mg	$158	In Stock	In Stock
100 mg	$239	In Stock	In Stock
500 mg	$597	-	In Stock
1 mL x 10 mM (in DMSO)	$47	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.89%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.
Targets&IC50	LeuRS (C. albicans):4.2 μM, A. fumigatus LeuRS:2 μM
In vitro	AN2718 inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM for A. fumigatus and C. albicans LeuRS, respectively)

Chemical Properties

Molecular Weight	168.39
Formula	C₇H₆BClO₂
Cas No.	174672-06-1
Smiles	OB1OCC2=CC(Cl)=CC=C12
Relative Density.	1.35 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (356.32 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.88 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9386 mL	29.6930 mL	59.3859 mL	296.9297 mL
5 mM	1.1877 mL	5.9386 mL	11.8772 mL	59.3859 mL
10 mM	0.5939 mL	2.9693 mL	5.9386 mL	29.6930 mL
20 mM	0.2969 mL	1.4846 mL	2.9693 mL	14.8465 mL
50 mM	0.1188 mL	0.5939 mL	1.1877 mL	5.9386 mL
100 mM	0.0594 mL	0.2969 mL	0.5939 mL	2.9693 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc