Powder: -20°C for 3 years
In solvent: -80°C for 2 years
AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
Description | AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM. |
Targets&IC50 | Dyrk pS421:0.192 μM, DYRK1B:7 nM |
In vitro | Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization[1]. |
Synonyms | 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine |
Molecular Weight | 300.36 |
Formula | C19H16N4 |
CAS No. | 1679330-37-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 120 mg/mL (399.52 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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AZ-Dyrk1B-33 1679330-37-0 蛋白酪氨酸激酶 细胞周期 DYRK Dual specificity tyrosine regulated kinase kinase syndrome mechanism cells resistance stress inhibit Inhibitor metabolic response undergoing Mirk-related AZDyrk1B33 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine Minibrain-related Dyrk1B AZ Dyrk1B 33 Dual specificity tyrosine phosphorylation regulated kinase AZ-Dyrk-1B-33 osteosarcoma inhibitor