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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3638 | Leukadherin-1 | Integrin , Complement System | |
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation. | |||
T14968 | Cinanserin hydrochloride | SQ 10643 | Influenza Virus , 5-HT Receptor |
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. | |||
T9218 | Andrograpanin | 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE | p38 MAPK |
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties. | |||
T38364 | MeOSuc-AAPV-AMC | MeOSuc-Ala-Ala-Pro-Val-AMC | |
MeOSuc-AAPV-AMC (MeOSuc-Ala-Ala-Pro-Val-AMC) is a tetrapeptide that is a fluorescent substrate for human leukocyte and porcine pancreatic elastase. | |||
TP1554L | HPV16 E7 (86-93) acetate | HPV16 E7 (86-93) acetate(160212-93-1 Free base) | Others |
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas. | |||
T2238 | Cariporide | HOE-642 | Sodium Channel |
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (... | |||
T21781 | A-286982 | Integrin | |
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1. | |||
T21729 | (±)-Lisofylline | Others | |
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent. | |||
T14676 | BMS-688521 | Integrin | |
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity. | |||
T24584 | P505-15 Acetate | PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate | Tyrosinase |
P505-15 Acetate is a selective inhibitor of spleen tyrosine kinase that acts by suppressing leukocyte immune function and inflammation and leading to a reduction in arthritis score and attenuated histological damage. | |||
T76844 | Abciximab | C7E3 | Integrin |
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa... | |||
T17157 | TRAF-STOP inhibitor 6877002 | CD40-TRAF6 inhibitor | NF-κB |
TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor), is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation... | |||
T0070 | Pentoxifylline | Oxpentifylline,PTX,BL-191 | HIV Protease , PDE , Adenosine Receptor , Autophagy |
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ... | |||
TP1168 | N-Formyl-Met-Leu-Phe-Lys | fMLFK | Others |
N-Formyl-Met-Leu-Phe-Lys (fMLFK) (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) ... | |||
T4115 | Auraptene | 7-geranyloxycoumarin | MMP , BACE |
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le... | |||
T1638 | N-Acetylneuraminic acid | Acide aceneuramique,NeuAc,Lactaminic acid | Others , Influenza Virus , Endogenous Metabolite |
N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown t... | |||
T6S1256 | Ruscogenin | NOS , NF-κB , NOD-like Receptor (NLR) | |
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ... | |||
T24771 | SCH-336 | SCH336,SCH 336 | Cannabinoid Receptor |
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1. SCH-336 red... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T24869 | Texasin | IR2,IR 2,IR-2 | |
Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase. |