homolog — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7953	BpV(HOpic)	bpV (HOpic)	PTEN
	BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).		PTEN
T7012	VO-Ohpic trihydrate	VO-Ohpic	PTEN , Autophagy
	VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.		PTEN , Autophagy
T3780	Oroxin B	Hypocretin-2	Apoptosis , PTEN , Antioxidant , PI3K , Autophagy
	Oroxin B (Hypocretin-2) has antioxidant activity.		Apoptosis , PTEN , Antioxidant , PI3K , Autophagy
TN1362	Afzelin	Kaempferol-3-O-rhamnoside	PTEN , p38 MAPK , TNF , Mitochondrial Metabolism , Antibacterial , Prostaglandin Receptor , Autophagy
	Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced d...
T6S2116	Ginkgolic acid C17:1		Phosphatase , PTEN
	1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.		Phosphatase , PTEN
T12075	ML-180	SR1848	Others
	ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .		Others
T6667	SF1670	PTP CD45 Inhibitor,PTPase CD45 Inhibitor	Phosphatase , PTEN , Autophagy
	SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.		Phosphatase , PTEN , Autophagy
T8954	ML179	ML-179	Others
	ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM.		Others
T38680	RJW100		Others
	RJW100 is a compound that acts as a potent agonist of liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1), exhibiting pEC50 values of 6.6 and 7.5, respectively. Additionally, RJW100 induces r...		Others
T64363	(Iso)-RJW100		Others
	(Iso)-RJW100 is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC 50 s of 6.4 and 7.2, respectively.		Others
T60194	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide		Histone Methyltransferase
	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide is a potent and selective Enhancer of Zeste Homolog 2 (EZH2) inhibitor with I...		Histone Methyltransferase
T6360	3-deazaneplanocin A HCl		Others , Histone Methyltransferase
	3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.		Others , Histone Methyltransferase
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
T10616	BRM/BRG1 ATP Inhibitor-1		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50...		Epigenetic Reader Domain
T10087	24-Norursodeoxycholic acid	nor-UDCA	Others
	24-Norursodeoxycholic acid (nor-UDCA) is a side chain-shortened C23 homolog of UDCA.It has shown potent anti-inflammatory, anti-cholestatic, and anti-fibrotic properties.It is a Ursodeoxycholic Acid derivative. It is sup...		Others
TP1936L1	RFRP3(human) acetate(311309-27-0 free base)		Neuropeptide Y Receptor
	RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced produ...		Neuropeptide Y Receptor
T29231	ZLD1039	ZLD-1039,ZLD 1039	Histone Methyltransferase
	ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 ...		Histone Methyltransferase
TP1899L1	Hemokinin 1 (human) acetate(491851-53-7 free base)		Neurokinin receptor
	Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has prolifera...		Neurokinin receptor
TP1937L1	RFRP-1 (human) acetate(311309-25-8 free base)		Neuropeptide Y Receptor
	RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduc...		Neuropeptide Y Receptor
T2S1635	3-Isomangostin		MTH1
	3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...		MTH1