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Oroxin B

Catalog No. T3780 CAS 114482-86-9

Synonyms: Hypocretin-2

Oroxin B (Hypocretin-2) has antioxidant activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Oroxin B, CAS 114482-86-9

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 110.00
1 mL * 10 mM (in DMSO)	In stock	$ 90.00

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Purity: 98.33%

Purity: 98.22%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Oroxin B (Hypocretin-2) has antioxidant activity.
Source	Natural Products > Lamiaceae > Scutellaria

Synonyms	Hypocretin-2
Molecular Weight	594.52
Formula	C27H30O15
CAS No.	114482-86-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 168.2 mM

References and Literature

1. Li DQ,et al. Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system. Anal Bioanal Chem. 2014 Mar;406(7):1975-84. 2. Qiu J1,et al. Molecular modeling reveals the novel inhibition mechanism and binding mode of three natural compounds to staphylococcal α-hemolysin.PLoS One. 2013 Nov 27;8(11):e820197. 3. Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathway of PI3K/Akt/mTOR in esophageal squamous cell carcinoma[J].

Citations

1. Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathway of PI3K/Akt/mTOR in esophageal squamous cell carcinoma. british journal of cancer. 2022 Nov;127(8):1424-1439. 2. Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma. British Journal of Cancer. 2022: 1-16. 3. Huang J, Wang C, Lu S, et al. Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity. Drug Design, Development and Therapy. 2021, 15: 4811-4825.

Related compound libraries

This product is contained In the following compound libraries：

Kinase Inhibitor Library HIF-1 Signaling Pathway Compound Library Chinese Pharmacopoeia Natural Product Library Anti-Ovarian Cancer Compound Library Endoplasmic Reticulum Stress Compound Library Stem Cell Differentiation Compound Library Anti-Cancer Metabolism Compound Library Reprogramming Compound Library Bioactive Compounds Library Max Oxidation-Reduction Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Oroxin B 114482-86-9 Apoptosis Autophagy oxidation-reduction PI3K/Akt/mTOR signaling Antioxidant PTEN PI3K inhibit MMAC1 Phosphoinositide 3-kinase Inhibitor Hypocretin-2 Phosphatase and tensin homolog inhibitor

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