Powder: -20°C for 3 years
In solvent: -80°C for 2 years
bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
Description | bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM). |
Targets&IC50 | PTEN:14 nM(Cell-free assay) |
In vitro | 1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1] |
Synonyms | bpV (HOpic) |
Molecular Weight | 347.235 |
Formula | C6H4K2NO8V |
CAS No. | 722494-26-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: 10 mM
DMSO: Insoluble
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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BpV(HOpic) 722494-26-0 PI3K/Akt/mTOR信号通路 PTEN MAPK/ERK Phosphatase and tensin homolog Inhibitor MMAC1 bpV (HOpic) inhibit PI3K/AKT signalling inhibitor