Home Tools
Log in


Catalog No. T7953   CAS 722494-26-0
Synonyms: bpV (HOpic)

bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
BpV(HOpic), CAS 722494-26-0
Please contact us for prices and availability for the specification of product you are interested at.
Product consultation
Get quote
Purity: 98%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
Targets&IC50 PTEN:14 nM(Cell-free assay)
In vitro 1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1]
Synonyms bpV (HOpic)
Molecular Weight 347.235
Formula C6H4K2NO8V
CAS No. 722494-26-0


Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 10 mM

DMSO: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dimchev GA, Al-Shanti N, Stewart CE.Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways.J Muscle Res Cell Motil. 2013 May;34(2):125-36. 2. Schmid A C , Byrne R D , Ramón Vilar, et al. Bisperoxovanadium compounds are potent PTEN inhibitors[J]. Febs Letters, 2004, 566(1-3):0-38.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Compound Library Autophagy Compound Library Anti-Lung Cancer Compound Library Inhibitor Library Kinase Inhibitor Library Stem Cell Differentiation Compound Library Apoptosis Compound Library Anti-Aging Compound Library Bioactive Compound Library Tyrosine Kinase Inhibitor Library

Related Products

Related compounds with same targets
Valinomycin Afzelin BpV(HOpic) VO-Ohpic trihydrate Ginkgolic acid C17:1 SF1670 Oroxin B Cucurbitacin B

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Average weight of animals
Dosing volume per animal
Number of animals
Step Two: Enter the in vivo formulation
% Tween 80
% ddH2O
Calculate Reset


Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box


Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box


Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.


Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.


BpV(HOpic) 722494-26-0 PI3K/Akt/mTOR信号通路 PTEN MAPK/ERK Phosphatase and tensin homolog Inhibitor MMAC1 bpV (HOpic) inhibit PI3K/AKT signalling inhibitor