dysfunction — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8348	Phentolamine		Adrenergic Receptor
	Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist		Adrenergic Receptor
T19777	ODQ		Apoptosis , Others , Guanylate cyclase
	ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.		Apoptosis , Others , Guanylate cyclase
T1635	Fenchlorphos	Ronnel,Dermafos	AChE , Parasite
	Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.		AChE , Parasite
TN4417	Larixyl acetate		Others
	Larixyl acetate is a bioactive chemical.		Others
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
TQ0091	LY2795050		Opioid Receptor
	LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM).		Opioid Receptor
T22671	CJ 033466		5-HT Receptor
	CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.		5-HT Receptor
T8405	Vardenafil hydrochloride		PDE
	Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes		PDE
T0096	Vardenafil	Vivanza,Levitra,Vardenafil hydrochloride	PDE
	Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...		PDE
TN1969	N-(p-Coumaroyl) serotonin		PDGFR
	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...		PDGFR
T11685	Isolongifolene	(-)-Isolongifolene	Apoptosis , Others
	Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative ...		Apoptosis , Others
T3410	Momordin Ic	Momordin 1c	Apoptosis , MAPK , PI3K
	Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. A...		Apoptosis , MAPK , PI3K
T5513	RO-3		P2X Receptor
	RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor		P2X Receptor
T5183	AUT1		Potassium Channel
	AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).		Potassium Channel
T8494	NS-3-008 hydrochloride	NS-3-008 HCl	Others
	NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).		Others
T4097	Vardenafil hydrochloride trihydrate	Vardenafil HCl Trihydrate,BAY38-9456	PDE
	Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.		PDE
T60080	TMPH	2,2,6,6-Tetramethylpiperidin-4-yl heptanoate	AChR
	TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.		AChR
T8390	Cefazolin		Others , Antibacterial , Antibiotic
	Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.		Others , Antibacterial , Antibiotic
T5645	Nerol	Cis-Geraniol,Neryl alcohol	Apoptosis , Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite , Antifungal
	Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
T1006	Propantheline bromide	Neopepulsan,Pro-Banthine,Neometantyl	AChR
	Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...		AChR