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20

Compounds

Cat No. Product Name Synonyms Targets
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T8158 Tilianin Others
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T7042 1,5-Isoquinolinediol PARP
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...
T9921 Infliximab TNF
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
T16724 Razuprotafib AKB-9778 Phosphatase , Others
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.
T3S1591 Notoginsenoside Fc Others , Autophagy
1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.
T7704 KY-226 Phosphatase
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T7502L PF 05089771 PF-05089771,PF05089771 Sodium Channel
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
T2058 Palosuran ACT-058362 GPR
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
T21902 ML351 Lipoxygenase
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).
T6237 Trelagliptin SYR-472 Proteasome , DPP-4
Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
T7912 (−)-Myrtenal (1R)-(−)-Myrtenal Others
(−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
T7502 PF 05089771 tosylate Sodium Channel
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8...
T3803 Specnuezhenide Nuzhenide,Nuezhenide Others , NF-κB , Wnt/beta-catenin
Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t...
TN1686 Ginsenoside Rg4 Antibacterial
Ginsenoside Rg4 is a natural product
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T1129 Benfotiamine Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate Others
Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.
TN7108 Urolithin C Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
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