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20

Compounds

Cat No. Product Name Synonyms Targets
T23101 O-3M3FBS Others
Inactive analog of m-3M3FBS (PLC activator)
T8581 Flecainide hydrochloride Others
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
T4573 Cyclothiazide GluR
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its response to glutamic acid (EC50 = 3.8 M).
T1186 Ifenprodil Tartrate Potassium Channel , NMDAR , iGluR
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T16348 NS5806 NS-5806 Potassium Channel
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM).
T23280 Ruthenium Red Ammoniated ruthenium oxychloride Calcium Channel
Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids ...
T16347 NS3623 Potassium Channel
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic e...
T15286 Flindokalner BMS-204352 Potassium Channel
Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) p...
T1434 Clarithromycin A-56268 P450 , ribosome , MRP , Antibacterial , Antibiotic , Autophagy
Clarithromycin (A-56268) is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor. The chemical classif...
T2451 GlyH-101 GlyH 101 CFTR , Autophagy
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
T7775 A2764 dihydrochloride Potassium Channel
A2764 dihydrochloride is a highly selective inhibitor of TRESK.
T4550 Ajmaline Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline Sodium Channel
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and...
T6541 Ibutilide Fumarate Corvert Fumarate,U70226E Calcium Channel , Sodium Channel
Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar...
T3574 Sematilide hydrochloride CK-1752A,CK-1752,Sematilide HCl Potassium Channel
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ...
T15758 Linopirdine DuP 996 Potassium Channel , TRP/TRPV Channel
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel...
T9009 ICA-105574 ICA,3-nitro-N-[4-phenoxyphenyl]-benzamide HER
ICA-105574 (ICA) is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
T7056 Dronedarone SR 33589 P450 , Potassium Channel , Calcium Channel , Sodium Channel , Adrenergic Receptor , AChR , Autophagy
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T15207 Eleclazine hydrochloride GS 6615 hydrochloride Sodium Channel
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
T17262 XE 991 dihydrochloride Others , Potassium Channel
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, r...
TP1858L Phe-Met-Arg-Phe, amide acetate Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase) Potassium Channel
Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.

Compounds

o-3M3FBS
T23101
Synonym:
Target: Others
Flecainide hydrochloride
T8581
Synonym:
Target: Others
Cyclothiazide
T4573
Synonym:
Target: GluR
Ifenprodil Tartrate
T1186
Synonym:
Target: Potassium Channel, NMDAR, iGluR
NS5806
T16348
Synonym: NS-5806
Target: Potassium Channel
Ruthenium Red
T23280
Synonym: Ammoniated ruthenium oxychloride
Target: Calcium Channel
NS3623
T16347
Synonym:
Target: Potassium Channel
Flindokalner
T15286
Synonym: BMS-204352
Target: Potassium Channel
Clarithromycin
T1434
Synonym: A-56268
Target: P450, ribosome, MRP, Antibacterial, Antibiotic, Autophagy
GlyH-101
T2451
Synonym: GlyH 101
Target: CFTR, Autophagy
A2764 dihydrochloride
T7775
Synonym:
Target: Potassium Channel
Ajmaline
T4550
Synonym: Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline
Target: Sodium Channel
Ibutilide Fumarate
T6541
Synonym: Corvert Fumarate,U70226E
Target: Calcium Channel, Sodium Channel
Sematilide hydrochloride
T3574
Synonym: CK-1752A,CK-1752,Sematilide HCl
Target: Potassium Channel
Linopirdine
T15758
Synonym: DuP 996
Target: Potassium Channel, TRP/TRPV Channel
ICA-105574
T9009
Synonym: ICA,3-nitro-N-[4-phenoxyphenyl]-benzamide
Target: HER
Dronedarone
T7056
Synonym: SR 33589
Target: P450, Potassium Channel, Calcium Channel, Sodium Channel, Adrenergic Receptor, AChR, Autophagy
Eleclazine hydrochloride
T15207
Synonym: GS 6615 hydrochloride
Target: Sodium Channel
XE 991 dihydrochloride
T17262
Synonym:
Target: Others, Potassium Channel
Phe-Met-Arg-Phe, amide acetate
TP1858L
Synonym: Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase)
Target: Potassium Channel
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TargetMol