congestive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5329	Trandolapril		Angiotensin-converting Enzyme (ACE)
	Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.		Angiotensin-converting Enzyme (ACE)
T1462	Captopril	SQ 14225,SQ-14534,SA333	RAAS
	Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.		RAAS
T0342	Carvedilol phosphate hemihydrate	Carvedilol phosphate,BM 14190 (phosphate hemihydrate)	VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
	Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T0154	Nebivolol hydrochloride	R 065824 hydrochloride,Nebivolol HCl,R-65824	Apoptosis , Adrenergic Receptor
	Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...		Apoptosis , Adrenergic Receptor
T3212	Digoxigenin		Others
	Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases		Others
T33600L	(Rac)-Naxifylline	(Rac)-Naxifylline（(Rac)-166374-49-8）	Others
	(Rac)-Naxifylline may be used to study congestive heart failure.		Others
T27596	Imazodan hydrochloride	CI914 HCl,CI-914 HCl,CI 914 HCl,Imazodan HCl	PDE
	Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure.		PDE
T1182	Levocarnitine propionate hydrochloride	Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261	Histamine Receptor
	Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.		Histamine Receptor
T1694	Oxypurinol	Oxipurinol	ROS , Xanthine Oxidase , Endogenous Metabolite
	Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.		ROS , Xanthine Oxidase , Endogenous Metabolite
T6595	Moexipril hydrochloride	Moexipril HCl,RS-10085,SPM 925,CI-925	Apoptosis , RAAS
	Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.		Apoptosis , RAAS
T0805	Quinapril hydrochloride	CI-906,PD-109452-2,Quinapril HCl	RAAS
	Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie...		RAAS
T16782	Rolofylline	KW-3902,MK-7418,KF-15372	Adenosine Receptor
	Rolofylline (KW-3902) is a selective adenosine A1 receptor antagonist used in the study of acute congestive heart failure and renal dysfunction, and in the study of neurodegenerative disorders.		Adenosine Receptor
T8462	Enoximone		PDE
	Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.		PDE
T27119L	(Rac)-Daglutril	SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid	Others
	(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ...		Others
T1670	Lanatoside C	Cedilanid,Ceglunate,Isolanid	ATPase , Virus Protease , Autophagy
	Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...		ATPase , Virus Protease , Autophagy
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T2530	Levosimendan	OR1259,OR1855	Potassium Channel , PDE , Carbonic Anhydrase , Autophagy
	Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without ...		Potassium Channel , PDE , Carbonic Anhydrase , Autophagy
T16444	PD-118057		Potassium Channel , HER
	PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential ...		Potassium Channel , HER
T35336	Furosemide sodium	Frusemide Sodium,Lasix	Na-K-Cl cotransporter
	Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity ...		Na-K-Cl cotransporter
T28191	NP-252	NP252
	NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.