antiallergic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63825	Antiallergic agent-1
	Antiallergic agent-1, an Src family kinase inhibitor, is a new and valuable lead compound with potential as an anti-allergic agent.
TN1712	Gossypin		NF-κB , S6 Kinase
	Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...		NF-κB , S6 Kinase
T3776	Rhapontigenin	Protigenin	P450 , Antibacterial , Antifungal
	Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R...		P450 , Antibacterial , Antifungal
T3254	PHYTOL	trans-Phytol,(E)-Phytol	Antibacterial , PPAR , Parasite
	PHYTOL (trans-Phytol) , a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects....		Antibacterial , PPAR , Parasite
T3979	Emedastine	LY188695,Emadine	Histamine Receptor
	Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...		Histamine Receptor
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T1035	Hesperidin	Hesperetin 7-rutinoside,Cirantin	Apoptosis , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
	Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
T6426	Buclizine dihydrochloride	Longifene,Buclina,Buclizine HCl,UCB-4445	5-HT Receptor , AChR , Histamine Receptor
	Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ...		5-HT Receptor , AChR , Histamine Receptor
T2335	Ebastine	Ebastel,LAS-W 090,Ebastin,Kestine,RP64305	Histamine Receptor
	Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss...		Histamine Receptor
T6488	Epinastine hydrochloride	Alesion,Epinastine HCl,WAL-801CL HCl,Elestat	5-HT Receptor , Histamine Receptor
	Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.		5-HT Receptor , Histamine Receptor
T15666	KP136	AL136	Others
	KP136 is an orally effective antiallergic compound (IC50: 76.1 μg/mL for histamine release and 63 ug/mL for degranulation).		Others
T2891	Ammonium glycyrrhizinate	Glycamil,Monoammonium glycyrrhizinate,Ammonium Glycyrrhizate,Monoammonium glycyrrhizinate hydrate,Glycyrram	Others
	Ammonium glycyrrhizinate (Glycyrram) has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.		Others
TWO2771	2-Adamantanol	Adamantan-2-Ol,2-Hydroxyadamantane	Others
	2-Adamantanol (2-Hydroxyadamantane) was used to synthesize antiallergic drug Mizolastine.		Others
T67953	Elbanizine		Others
	Elbanizine showed antiallergic, antiasthmatic, antihistaminic, and spasmolytic activity.		Others
T68128	Picumast
	Picumast shows antiallergic activity and can be utilized in the treatment of asthma. Picumast may be used in the treatment of therapeutic allergic airway diseases.
T3S2027	Rubusoside		Others
	1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties.		Others
T14326	AS-35		Others
	AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum. With IC50 values of 8 nM, 4 nM and 3 nM, respectively. It has antiallergi...		Others
T4566	Lodoxamide	Lodoxamidum	GPR , Histamine Receptor
	Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.		GPR , Histamine Receptor
T0795	Rutin	Quercetin 3-O-rutinoside,Rutoside	Beta Amyloid , Prostaglandin Receptor , Autophagy
	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.		Beta Amyloid , Prostaglandin Receptor , Autophagy
TN2429	Capsiate		Antioxidant , TRP/TRPV Channel
	Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemic, and inhibitory angiogenic activity.		Antioxidant , TRP/TRPV Channel