anti-ulcer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T2833	Dehydrocostus Lactone	Epiligulyl oxide,(-)-Dehydrocostus lactone	IκB/IKK
	Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.		IκB/IKK
T4510	Polaprezinc	Zinc L-carnosine	Others
	Polaprezinc is an bioavailable chelate comprised of zinc and L-carnosine, known for its gastrointestinal protective properties, as well as its anti-ulcer, antioxidant, and anti-inflammatory effects.		Others
TN1568	Deoxyartemisinin	2-deoxyartemisinin	Antifection
	Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria.		Antifection
T12215	Nexopamil racemate	(Rac)-Nexopamil	Calcium Channel , 5-HT Receptor
	Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.		Calcium Channel , 5-HT Receptor
T5008	Teprenone	Tetraprenylacetone,Geranylgeranylacetone	HSP
	Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).		HSP
TN2233	Spathulenol		Antioxidant , Antifungal
	Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant acti...		Antioxidant , Antifungal
T10872L	CP 96021		5-HT Receptor
	CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma.		5-HT Receptor
T77618	COX-2-IN-34		COX
	COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.		COX
TN6577	Bletilloside A	3-Methoxyshancigusin I	Others
	Bletilloside A（3-Methoxyshancigusin I） is a novel glucoside isolated from tubers of striped alfalfa with anti-gastric ulcer activity.		Others
T6548	Irsogladine	Dicloguamine	PDE , AChR
	Irsogladine (Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.		PDE , AChR
T6710	Troxipide	Aplace	Others
	Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.		Others
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
T77617	MMP-9-IN-6		MMP
	MMP-9-IN-6 is an MMP-9 inhibitor with an IC50 value of 50 μM and good anti-ulcer efficacy.MMP-9-IN-6 has potential anti-tumor activity and can be used to study tissue remodeling, wound repair and atherosclerosis.		MMP
T1639	Amlexanox	CHX3673,Amoxanox,AA673	IL Receptor , FGFR , Others , IκB/IKK
	Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexan...		IL Receptor , FGFR , Others , IκB/IKK
T62396	KB-5492 free base
	KB-5492 free base is a potent and selective sigma receptor inhibitor, inhibiting [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 value of 3.15 μM. KB-5492 free base is an anti-ulcer agent.
T1562	Rebamipide	Proamipide,OPC12759	Free radical scavengers , COX , Prostaglandin Receptor
	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...		Free radical scavengers , COX , Prostaglandin Receptor
T19763	Cetraxate hydrochloride	DV-1006,DV 1006,Cetraxate HCl,DV1006	Serine/threonin kinase
	Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.		Serine/threonin kinase