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Search Result

Search Results for " taf "

44

Compounds

3

Natural Products

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T36685 TAF 10 Peptide
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity. One vial of this peptide may be used as a methyltransferase acceptor peptide for more than 200 reactions at 15 μM.
T77135 Tafasitamab MOR00208,XmAb5574,Tafasitamab-cxix Apoptosis , Immunology/Inflammation related
Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma.
T7182 Metaflumizone BAS-320I Sodium Channel , Parasite
Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.
T9339 Stafia-1 STAT
Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
T16724 Razuprotafib AKB-9778 Phosphatase , Others
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.
T27122 Dasantafil SCH446132,SCH-446132,SCH 446132 PDE
Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.
T27335 Floctafenine RU 15750,R-4318,R 4318,RU-15750,R4318 COX
Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet effects of aspirin.Floctafenine has analgesic activity and is ...
T13083L Tafenoquine Succinate WR 238605 (Succinate) Others
Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.
T4565 Tafamidis Fx-1006A Others
Tafamidis (Fx-1006A) is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 278 nM) to stabilize the TTR di...
T28911 Tafetinib SIM-010603,SIM010603,SIM 010603 Tyrosine Kinases
Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity.
T61699 Osunprotafib AC 484,Osunprotafib,AC484,ABBV-CLS-484 Phosphatase
ABBV-CLS-484 (Osunprotafib) is a potent PTPN2 inhibitor with subnanomolar activity and antitumor activity that enhances T-cell anti-tumor immunity.ABBV-CLS-484 can be used for the treatment of neoplasms, esophageal cance...
T6349 Sitafloxacin Hydrate DU-6859a,DU6859a hydrate Antibacterial , Antibiotic
Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.
T2621 Rostafuroxin PST 2238 ATPase , RSV
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.
T6349L Sitafloxacin DU6859,DU 6859,DU 6859A,Sitafloxacin anhydrous,DU-6859,DU6859A,DU-6859A
Sitafloxacin, a new generation of broad-spectrum oral fluoroquinolones, is highly effective against many Gram-positive, Gram-negative, and anaerobic clinical isolates (including strains resistant to other fluoroquinolone...
T9646 Stafib-2 STAT
Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM, respectively.Stafib-2 has poor cell permeability.
T7582 tafamidis meglumine Fx-1006A Others
Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade
T66574 Sodium tetrakis (pentafluorophenyl)-borate
sodium tetrakis (pentafluorophenyl)-borate is a useful organic compound for research related to life sciences and the catalog number is T66574.
T126040 Imbricataflavone A
Imbricataflavone A is a useful organic compound for research related to life sciences and the catalog number is T126040.
T31684 Etafedrine HCl Novedrin hydrochloride,Nethamine,Nethamine hydrochloride,Etafedrine hydrochloride,Menetyl,Novedrin
Etafedrine HCl, named Nethaprin, is a long-acting bronchodilator.
T20142 Tafluprost acid UNII-WTV8EPZ396
Tafluprost acid is a selective agonist at the prostaglandin F receptor.
T37849 Butafosfan
Butafosfan is an organic phosphorus supplement that is given, most commonly with cyanocobalamin, to cattle, swine, horses, and poultry for the prevention or treatment of deficiencies. When given with cyanocobalamin, buta...
T70150 Capstafin
Capstafin is a highly potent and selective inhibitor of STAT5b.
T70149 PomCapstafin
PomCapstafin is a prodrug of Capstafin, acting as a potent, selective STAT5b inhibitor.
T31685L Etafenone LG-11457,LG 11457,LG11457,Etafenonum
Etafenone is a vasodilator for the therapy of anigna pectoris.
T28760 Setafrastat
Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.
T73739 Pomstafib-2
Pomstafib-2, a potent and selective inhibitor of STAT5b, reduces pSTAT5b expression and effectively induces apoptosis [1] [2].
T31685 Etafenone HCl NSC-166350,L.G. 11,457 hydrochloride,NSC166350,NSC 166350,Etafenone hydrochloride,Coronabason
Etafenone HCl is a vasodilator.
T25090 Antafenite R8193,R 8193,R-8193
Antafenite is an anthelminthic agent.
T24838 Stafib-1 Stafib 1,Stafib1 STAT
Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.
T15243 Ertiprotafib PTP 112 Phosphatase , PPAR
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).
T76843 Tebentafusp
Tebentafusp (IMCgp100) is a bispecific fusion protein designed to target the gp100 peptide-HLA-A*02:01 complex, a melanoma-associated antigen. It directs T cells towards melanoma cells expressing gp100 through a high-aff...
T75287 Sitafloxacin monohydrate
Sitafloxacin (DU6859a) monohydrate is a potent, oral fluoroquinolone antibiotic with antichlamydial and broad-spectrum antibacterial activities against gram-positive, gram-negative, anaerobic bacteria, and atypical patho...
T13083 Tafenoquine WR 238605 Others
Tafenoquine is an 8-aminoquinoline,and is an agent of anti-malarial prophylactic.
T37956 Tafluprost ethyl amide
Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide reduces intraocular pressure (IOP) and affects eyelash growth. Tafluprost ethyl amide can be used in anti-glaucoma eye drops and cosmetics.
T28912 Tafluposide F 11782,F-11782,F11782
Tafluposide is a DNA topoisomerase inhibitor with anti-tumor activity.
T19846 Butafenacil
Butafenacil is an effective anemia inducer.
T79049 Tegeprotafib PTPN2/1-IN-1 Phosphatase
Tegeprotafib (PTPN2/1-IN-1) (Compound 124) is an orally active inhibitor targeting both PTPN2 and PTPN1B, displaying potent IC50 values at 4.4 nM for PTPN2 and 1-10 nM for PTPN1B, respectively [1].
T75286 Sitafloxacin hydrochloride
Sitafloxacin hydrochloride (DU6859a), a potent fluoroquinolone antibiotic with oral activity, demonstrates antichlamydial activity and a broad antibacterial spectrum against gram-positive, gram-negative, and anaerobic ba...
T76974 Tafolecimab
Tafolecimab (IBI-306), a human IgG2 monoclonal antibody, specifically targets and binds to PCSK-9, thus inhibiting PCSK-9-mediated endocytosis of the LDL receptor. This action enhances the clearance of LDL-C, resulting i...
T38256 Pentafluorobenzenesulfonyl fluorescein Others
Pentafluorobenzenesulfonyl fluorescein itself no fluorescence, but were in the H2O2 in sulfonyl key fluoresce when hydrolyzed. Pentafluorobenzenesulfonyl fluorescein is often treated as selective H2O2 sensors, can be use...
T124921 Crotafoline
Crotafoline is a useful organic compound for research related to life sciences and the catalog number is T124921.
T35917 Stafia-1-dipivaloyloxymethyl ester
Stafia-1-dipivaloyloxymethyl ester (compound 27) demonstrated a dose-dependent reduction in pSTAT5a expression (0-200 μM) while showing no discernible effect on pSTAT5b[1].
T124187 Euchrestaflavanone A
Euchrestaflavanone A is a useful organic compound for research related to life sciences and the catalog number is T124187.
T72593 Antiviral agent 9
Antiviral agent 9 exhibits potent efficacy against HIV-1 with an EC50 value of 0.006 nM, indicating extremely low concentrations are sufficient to inhibit the virus. Additionally, it demonstrates a selectivity index (SI)...

Compounds

TAF 10 Peptide
T36685
Synonym:
Target:
Tafasitamab
T77135
Synonym: MOR00208,XmAb5574,Tafasitamab-cxix
Target: Apoptosis, Immunology/Inflammation related
Metaflumizone
T7182
Synonym: BAS-320I
Target: Sodium Channel, Parasite
Stafia-1
T9339
Synonym:
Target: STAT
Razuprotafib
T16724
Synonym: AKB-9778
Target: Phosphatase, Others
Dasantafil
T27122
Synonym: SCH446132,SCH-446132,SCH 446132
Target: PDE
Floctafenine
T27335
Synonym: RU 15750,R-4318,R 4318,RU-15750,R4318
Target: COX
Tafenoquine Succinate
T13083L
Synonym: WR 238605 (Succinate)
Target: Others
Tafamidis
T4565
Synonym: Fx-1006A
Target: Others
Tafetinib
T28911
Synonym: SIM-010603,SIM010603,SIM 010603
Target: Tyrosine Kinases
Osunprotafib
T61699
Synonym: AC 484,Osunprotafib,AC484,ABBV-CLS-484
Target: Phosphatase
Sitafloxacin Hydrate
T6349
Synonym: DU-6859a,DU6859a hydrate
Target: Antibacterial, Antibiotic
Rostafuroxin
T2621
Synonym: PST 2238
Target: ATPase, RSV
Sitafloxacin
T6349L
Synonym: DU6859,DU 6859,DU 6859A,Sitafloxacin anhydrous,DU-6859,DU6859A,DU-6859A
Target:
Stafib-2
T9646
Synonym:
Target: STAT
tafamidis meglumine
T7582
Synonym: Fx-1006A
Target: Others
sodium tetrakis (pentafluorophenyl)-borate
T66574
Synonym:
Target:
Imbricataflavone A
T126040
Synonym:
Target:
Etafedrine HCl
T31684
Synonym: Novedrin hydrochloride,Nethamine,Nethamine hydrochloride,Etafedrine hydrochloride,Menetyl,Novedrin
Target:
Tafluprost acid
T20142
Synonym: UNII-WTV8EPZ396
Target:
Butafosfan
T37849
Synonym:
Target:
Capstafin
T70150
Synonym:
Target:
PomCapstafin
T70149
Synonym:
Target:
Etafenone
T31685L
Synonym: LG-11457,LG 11457,LG11457,Etafenonum
Target:
Setafrastat
T28760
Synonym:
Target:
Pomstafib-2
T73739
Synonym:
Target:
Etafenone HCl
T31685
Synonym: NSC-166350,L.G. 11,457 hydrochloride,NSC166350,NSC 166350,Etafenone hydrochloride,Coronabason
Target:
Antafenite
T25090
Synonym: R8193,R 8193,R-8193
Target:
Stafib-1
T24838
Synonym: Stafib 1,Stafib1
Target: STAT
Ertiprotafib
T15243
Synonym: PTP 112
Target: Phosphatase, PPAR
Tebentafusp
T76843
Synonym:
Target:
Sitafloxacin monohydrate
T75287
Synonym:
Target:
Tafenoquine
T13083
Synonym: WR 238605
Target: Others
Tafluprost ethyl amide
T37956
Synonym:
Target:
Tafluposide
T28912
Synonym: F 11782,F-11782,F11782
Target:
Butafenacil
T19846
Synonym:
Target:
Tegeprotafib
T79049
Synonym: PTPN2/1-IN-1
Target: Phosphatase
Sitafloxacin hydrochloride
T75286
Synonym:
Target:
Tafolecimab
T76974
Synonym:
Target:
Pentafluorobenzenesulfonyl fluorescein
T38256
Synonym:
Target: Others
Crotafoline
T124921
Synonym:
Target:
Stafia-1-dipivaloyloxymethyl ester
T35917
Synonym:
Target:
Euchrestaflavanone A
T124187
Synonym:
Target:
Antiviral agent 9
T72593
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TQ0203 Tafluprost MK2452,AFP-168 Prostaglandin Receptor
Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.
TN4028 Euchrestaflavanone B PARP , Antifection
Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanone B may function by inhibiting oncogenic disease, at least ...
T26111 Robustaflavone
Robustaflavone is a naturally occurring biflavanoid isolated from Rhus succedanea and is a hepatitis B virus replication inhibitor.

Natural Products

Tafluprost
TQ0203
Synonym: MK2452,AFP-168
Target: Prostaglandin Receptor
Euchrestaflavanone B
TN4028
Synonym:
Target: PARP, Antifection
Robustaflavone
T26111
Synonym:
Target:

Recombinant Proteins

Species：
Human (10)
Mouse (3)
Expression System：
HEK293 Cells (10)
E. coli (3)
Tag：
His (3)
C-hFc (2)
hFc (2)
C-6xHis (1)
His, Avi (1)
N-10xHis, C-Myc (1)
N-6xHis (1)
N-GST (1)
hFc, Avi (1)
Cat No. Product Name Species Expression System
TMPY-02295 IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.5 kDa and the accession number is Q16270.
TMPY-02533 IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q16270.
TMPK-01027 IGFBP-7 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 ...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 ...
TMPY-02296 IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.9 kDa and the accession number is Q16270.
TMPY-06848 IGFBP-7 Protein, Human, Recombinant (K95R, His) Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (K95R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.59 kDa and the accession number is Q16270.
TMPJ-01166 IGFBP-7 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ...
TMPY-06644 IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 54.98 kDa and the accession number is Q16270.
TMPY-06649 IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.37 kDa and the accession number is Q16270.
TMPY-02946 TAFA2/FAM19A2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
FAM19A2 belongs to the FAM19/TAFA family. FAM19/TAFA family members are chemokine-like proteins. The biological functions of TAFA family members remain to be determined, but there are a few tentative hypotheses. First, T...
TMPH-02175 TAF5L Protein, Human, Recombinant (GST) Human E. coli
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex....
TMPH-02576 TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation.
TMPJ-01279 TAFA4 Protein, Human, Recombinant (His) Human E. coli
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine res...
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