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Floctafenine

Catalog No. T27335 CAS 23779-99-9

Synonyms: RU 15750, R-4318, R 4318, RU-15750, R4318

Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet effects of aspirin.Floctafenine has analgesic activity and is used in the study of pain.

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Floctafenine, CAS 23779-99-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 293.00
5 mg	In stock	$ 722.00
10 mg	In stock	$ 987.00
25 mg	In stock	$ 1,520.00
50 mg	In stock	$ 1,980.00
100 mg	In stock	$ 2,500.00

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Purity: 99.31%

Purity: 98.65%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	RU 15750, R-4318, R 4318, RU-15750, R4318
Molecular Weight	406.36
Formula	C20H17F3N2O4
CAS No.	23779-99-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. P Giuseppe, et al. Floctafenine: a valid alternative in patients with adverse reactions to nonsteroidal anti-inflammatory drugs. Ann Allergy Asthma Immunol. 1997 Jan;78(1):74-8. 2. Gehan Hegazy Hegazy, et al. Synthesis of some floctafenine derivatives of expected anti-inflammatory/analgesic activity. Arch Pharm (Weinheim). 2005 Aug;338(8):378-84. 3. R Maenthaisong, et al. Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects.Int J Immunopathol Pharmacol. Apr-Jun 2013;26(2):403-17. 4. Walash M, Belal F, Eid M, el-Abass SA. Simultaneous HPLC determination of thiocolchicoside and glafenine as well as thiocolchicoside and floctafenine in their combined dosage forms. J Chromatogr Sci. 2011 Feb;49(2):159-64.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Floctafenine 23779-99-9 Immunology/Inflammation Neuroscience COX RU 15750 RU15750 R-4318 R 4318 RU-15750 R4318 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.